October 3, 2017 6:18pm

As I had stated in the pre-open post, “… there are too many cross-currents and sentiment, although good yesterday remains in the “danger zone,” and therefore implies a negative forecast in the short-term.”

And, “the IBB indicated up +2.97% for the past five (5) sessions – it could be time or be close to a falter” - then closed down -0.23%

 

Pre-open indications: 4 hits and 3 miss (by pennies)

Out and about: Dimension Therapeutics (DMTX) has accepted Ultragenyx Pharmaceutical (RARE), a $151 million deal for $6 per share. The offer beats Regenxbio’s (RGNX) $3.41 per share. RARE will cover Dimension’s $2.85 million termination fee to RGNX for reneging on the earlier agreement.

 

The truths of “our” universe are reported - here!

I answer one question, in which company should investors commit and keep their money. In the grip of rotating cycles and disparaging trends, what is the price of sector knowledge – a subscription!  


 

Tuesday’s results have implications to Wednesday’s sector activity as a daily report may say little or a lot and it serves as insurance that all indications are being examined and evaluated!

 

 

Henry’omics:

From the pre-open’s newsletter “tread lightly … As there are too many cross-currents and it’s hard to discern whether investors should be buying, selling or holding.  Profit in your account is better than an algorithms’ calculation or an ETFs basket. Sentiment, although good yesterday remains in the “danger zone,” and therefore implies a negative forecast in the short-term.”

These are days when investors forget or don't appreciate the risks that the sector faces … Are investors chasing share pricing growth?

I’d be concerned … the iShares NASDAQ Biotechnology (IBB) indicated up +2.97% for the past five (5) sessions – it could be time or be close to a “falter”:

·         Monday was up +1.51%

·         Friday +0.92%

·         Thursday +$0.46%

·         Wednesday +0.57%

·         Tuesday -0.93%

·         Last Monday +0.44%

 

Pre-open indications: 4 hits and 3 miss

·         Cesca Therapeutics (KOOL) closed up +$1.22 – hit;

·         Cellectis SA (CLLS) closed down -$0.34 – hit;

·         Histogenics (HSGX) closed up + $0.05 – hit;

·         Intrexon (XON) closed +$0.06 – miss;

·         MiMedx (MDXG) closed down -$1.03 – miss;

·         uniQure N.V.  (QURE) closed down -$0.36 – hit;

·         Vericel (VCEL) closed up +$0.10 – miss;

 

Out and about:

After weighing buyout offers, Cambridge gene therapy firm Dimension Therapeutics (DMTX) has accepted the superior proposal — a $151 million deal that will allow the company to maintain a local presence. DMTX said it had agreed to be acquired by California-based Ultragenyx Pharmaceutical (RARE) for $6 per share. That offer beat out one from Rockland, Maryland-based Regenxbio Inc. (RGNX), which announced in late August that it had struck a deal to acquire Dimension for $3.41 per share. RARE will cover DMTX’s $2.85 million termination fee to RGNX for reneging on the earlier agreement.

 

Some of MY working trend lines or indications:

The greatest volume to the downside:  CAPR, MDXG, IMUC, NWBO and JUNO

Upside volume was weighted to:  KOOL, SGMO, VCEL, BLUE and CYTX

Biggest $ downside: RGNX (-$1.50), ONCE (-$1.19), MDXG (-$1.03), JUNO (-0.64) and BLCM (-$0.52)

Largest $ upside:  BLUE (+$2.10), KOOL (+$1.22), SGMO (+$0.55), ADRO (+0.20) and VCEL (+$0.10)

Flat:  KITE and RENE.L

 

 

Shaking the tree:

VCEL was up +$0.05 post Monday’s -$0.15 after Friday’s +$0.40 after Thursday’s  +$0.10 after Wednesday’s +$0.60 – I wouldn’t be surprised by a financing in future and soon …

As HSGX closed up +$0.05 after Monday’s flat again at $1.98 while AXGN closed down again -$0.50 following Monday’s -$0.25 after Friday’s +0.35 and MDXG was down -$1.03 after Monday’s +$0.91 … the merry-go-round turns and burns;

Even AGTC was up again +$0.05 after Monday’s +$0.15 … how long will this upside last? I haven’t seen or heard of ANY officer buys … Don’t TRUST this upside …!!

BSTG was down -$0.009 – if one can’t say ANYTHING positive about this company – why say it at all … BLAME management for their thoroughly depreciated predicament!

AST was down -$0.15 after Monday’s +$0.20 while mothership BTX was up +$0.05 after Monday’s -$0.05 … they both NEED cash to prop their balance sheets

CAPR closed down -$0.17 after Monday’s  +$0.42 post Friday’s +$0.80 – somethings up or amiss by these gyrations - CAPR can’t keep fooling investors for long with their brand of hype…

Cellectis S.A. (CLLS) fell -$0.34 as I projected in the pre-open post… after Monday’s pop of +$0.53, as I had stated … time to say good-bye for a while;

Immuno-oncologists - JUNO was down -$0.64 after Monday’s +$0.88 after Friday’s +$0.41 following Thursday’s +$1.77 post Wednesday’s +$0.63; KITE was flat at $179.79 down -$0.02 while BLCM was down -$0.52 after Monday’s  +$0.26 after Friday’s -$0.02 and VSTM was recharged again +$0.07 after Monday’s +$0.08 after Friday’s +$0.02

ATHX was down -$0.01 after Monday’s  +$0.13 after Friday’s -$0.07 post Thursday’s  -$0.07 following being down -$0.25 as many question their cash position going forward and their clinical “manufacturing” issues as trials continue …

RGNX was down -$1.50 but, is opting to back away from a deal to buy Dimension Therapeutics Inc. (DMTX). RGNX had announced plans to buy Dimension in an all-stock transaction.  Any time one has a doubt – wait, RGNX usually rebounds … by walking they receive $2.85 M …

SGMO was up again +$0.55 after Monday’s +$1.20 after Friday’s +$0.65 while ONCE was down -$1.19 after Monday’s +$0.21 after Friday’s -$0.07 as BLUE jumped +$2.10 after Monday’s drop of -$11.90 after Friday’s -$3.80

FATE is back traveling up again +$0.05 after Monday’s +$0.21 as MESO dropped -$0.03 following Monday’s +$0.32

CYTX was up +$0.01 after Monday’s $0.358 while another criminal, OSIR was up +$0.06 after being down -$0.06

PSTI is on the losing side of the trade -$0.06, when will it ever learn – it has to be considered trustworthy by shareholders

 

 

The advance/decline line scenario of 43 SCGT & RT covered companies:   

·         The first hour was barely positive with an A/DL of 20/19 and 4 flats;

·         The 10:30 am was negative  with an A/DL of 9/30 and 2 flats;

·         The mid-day was a negative with an ADL of 16/22 and 5 flats;

·         The close was negative with an A/DL of 18/23 and 2 flats;

 

 

Daily analytics:

U.S. stock benchmark indexes all continued to set fresh records on Tuesday while the small-caps index Russell 2000 (RUT) +0.17% treaded water at 1510.

·         The S&P 500 was up +0.22% claim its sixth consecutive session of gains to end at 2534.5. 

·         The NASDAQ rose 0.2% to close at 6531.7.

·         The Dow advanced more than 80 (+0.37%) points to close at 22641.

 

The CBOE Volatility Index (VIX) widely considered the best gauge of fear in the market; Tuesday traded at 9.57, up +1.27 …

  • Monday traded at 9.45, down -0.63% … after Friday traded at 9.51, down -0.42% after Thursday traded at 9.55, down -3.24% after Wednesday traded at 9.87, down -2.95% after last Tuesday traded at 10.127, down -0.39%

 

Welcome to another day of the sector’s roller coaster …

… The iShares Russell 2000 (IWM) indicated:

·         Tuesday was up +0.21%

·         Monday +1.23

·         Friday +20%

·         Thursday +0.28%

·         Wednesday+1.96%

·         Last Tuesday +0.32%

 

… The iShares NASDAQ Biotechnology (IBB) indicated:

·         Tuesday was down -0.23%

·         Monday +1.51%

·         Friday +0.92%

·         Thursday +$0.46%

·         Wednesday +0.57%

·         Last Tuesday -0.93%

 

 

The count - decliners versus gainers:

……. look at the differences in the spreads as decliners jump and %

·         Tuesday’s decliners ranged from -0.45% <ONVO -$0.01> to -8.05% <MDXG -$1.03> in 23 equities;

·         Monday’s decliners ranged from -0.01% <KITE -$0.02> to -8.66% <BLUE -$11.90> in 14 equities;

·         Friday’s decliners ranged from -0.08% <ONCE -$0.07> to -5.15% <OSIR -$0.25> in 14 equities;

·         Thursday’s decliners ranged from -0.16% <RGNX -$0.05> to -3.29% <BSTG -$0.0105> in 14 equities;

·         Wednesday’s decliners ranged from -0.23% <QURE -$0.02> to -10.20% <ATHX -$0.25> in 13 equities;

·         Last Tuesday’s decliners ranged from -0.05% <XON -$0.01> to -9.36% <OPXA -$0.10> in 23 equities;

Versus

… Look at the percentage’s (%) and spreads …

·         Tuesday’s gainers ranged from +0.31% <XON +$0.06> to +33.98% <KOOL +$1.22> in 18 equities;

·         Monday’s gainers ranged from +0.24% <ONCE +$0.21> to +13.86% <CAPR +$0.42> in 26 equities;

·         Friday’s gainers ranged from +0.04% <KITE +$0.08> to +35.87% <CAPR +$0.30> in 23 equities;

·         Thursday’s gainers ranged from +0.03% <KITE +$0.05> to +3.13% <CUR +$0.04> in 24 equities;

·         Wednesday’s gainers ranged from +0.02% <KITE +$0.04> to +12.24% <VCEL +$0.60> in 30 equities;

·         Last Tuesday’s gainers ranged from +0.18% <KITE +$0.33> to +5.30% <BLFS +$0.28> in 17 equities;

 

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.