February 7, 2018 5:51pm

Sector intelligence and perspective


The “machines” are still at work

The sector opened up, stayed up to the mid-day and closed to an upside while the indexes dived around 3 p.m.


Watch out below tomorrow!

... While the IBB (+0.05%), XBI (+0.40%), IWM (+0.10%) dived yet closed up with the XLV (-0.07%) and NASDAQ (-0.63.9 or -0.90%) diving


Out and about:

Adverum Biotechnologies (ADVM) proposes offering … https://www.regmedinvestors.com/articles/10132

Biostage (BSTG) finally names a new chairman of board after prodding as I had previously reported a Form 6 missing name …


Wednesday’s results have implications to Thursday’s sector activity as a daily report may say little or a lot and it serves as insurance that all indications are being examined and evaluated!



From the pre-open’s newsletter, “… after a wild sector swing, the market jitters after a bounce back representing an awakening for investors and companies as to who owns their shares? As algorithms and ETFs remind us of their leverage in pricing and exposure to volatility; these are just the beginnings of reverberations.”

As I stated, “The rapidity of the sell-off and the resulting buy-up is ALSO an indicator of DANGER – check your fundamentals!”

Stronger sector tops tend to be a process, not an event as a big tailwind is bound to turn into a headwind.

The CBOE Volatility index — widely considered the best gauge of fear in the market — has also been all over the map this week. On Monday, it more than doubled from 17.34 to 37.32. It also hit 50 on Tuesday before closing at 29.98. On Wednesday, it traded at 27.73.

Watch your "tops" in the a.m. - I percieve some craters!!



The advance/decline line scenario of 40 SCGT & RT covered companies:   

·         The open was positive with an A/DL of 26/11 and 4 flat ;

·         The mid-day continued positive with an A/DL of 24/14 and 2 flat;

·         The close was positive  with an A/DL of 25/13 and 2 flat;



MY working trend lines:

The greatest volume to the downside:  MDXG, IMUC, ONVO, ATHX and FATE

Upside volume was weighted to:  JUNO, SGMO, XON, BLUE and VSTM

Biggest $ downside:  MDXG (-$0.66), ONCE (-$0.43), AXGN (-$0.20), OSIR (-$0.13) and BCLI (-$0.11)

Largest $ upside:  BLUE (+$5.00), SGMO (+$2.45), RGNX (+1.00), RENE.L ($1.00) and STML (+$0.75)

Flat:  VCEL and ISTO



Out and about:

Gene therapy companies rebounded in the seventh (7) session after a five (5) session downdraft due to possible risks of high systemic dosing of AAV – the players … ONCE (-$0.43), BOLD (-$0.02) and SLDB (-$0.36),  were down as AGTC ($0.20), ADVM (+$0.20), AVXS (+$1.34), BLUE (+$5.00), RGNX (+$1.00), and QURE (+$0.50) ran to the upside

The stem cell companies, ATHX (-$0.02), AST (-$0.05), BTX (-$0.02) and CAPR (-$0.06) closed down as MESO (+$0.16), CLBS (+$0.23), PSTI (+$0.06), RENE.L (+$1.00 after a 1-for-100 reverse) and FCSC (+$0.01) closed to the upside

The immune-oncology group, BLCM (+$0.61), CLLS (+$0.05), JUNO (+$0.41), SGMO (+$2.45), STML (+$0.75) and VSTM (+$0.06) were rolling upward as FATE -$0.01) was down

While AXGN (-$0.20), MDXG (-$0.66), OSIR (-$0.13) was down while VCEL (+$0.00) was flat and HSGX (+$0.11) saw the sun shine …


Biostage (OTCQB: BSTG) has appointed Jason Jing Chen, Senior Vice President of Business Development of Digitone Group, and CEO of its subsidiary DST Robotics Co Ltd., as Chairman of Biostage's Board of Directors replacing John F Kennedy. Always late with company specifics (if any) and changes … let’s see how they explain in my OPINION the dramatic “fleecing” of shareholders in the conference call?



Daily analytics:

U.S. stocks finished lower after failing to defend intraday gains Wednesday as investors struggled to adjust to an investment environment marked by both rising bond yields and signs of inflation. Recent trading has seen huge swings in both directions, though the dominant move over the past week has been lower, something analysts said was to be expected after Wall Street scored big gains in January and throughout 2017.

·         The Dow slid 19.42 points to 24,893.35, after bungee-jumping a 500-point range during the session.

·         The S&P 500 fell 13.48 points, or 0.5%, to 2,681.66.

·         The NASDAQ shed 63.90, 0.9%, to 7,051.98.


The CBOE Volatility Index (VIX) widely considered the best gauge of fear in the market, Wednesday traded at 27.73, down -7.51% …

  • Tuesday traded at 29.98, down -19.67% after Monday traded at 37.32, up +20.01 or +115.6% after Friday traded at 17.21, up +27.77% after Thursday traded at 13.47, down -0.52% and last Wednesday traded at 13.54, down -8.45% …


Welcome to another day of the sector’s roller coaster …

… The iShares Russell 2000 (IWM) indicated:

·         Wednesday was up +0.10%

·         Tuesday +1.61%

·         Monday -3.84%

·         Friday -1.93%

·         Thursday +0.32%

·         Last Wednesday -0.48%


… The iShares NASDAQ Biotechnology (IBB) indicated:

·         Wednesday was up +0.05%

·         Tuesday +2.03%

·         Monday -4.42%

·         Friday -1.61%

·         Thursday -0.09%

·         Last Wednesday -1.88%



The count - decliners versus gainers:

……. look at the differences in decliners:

·         Wednesday’s decliners ranged from -0.03% <CYTX -$0.00> to -4.19% <CUR -$0.07> in 13 equities;

·         Tuesday’s decliners ranged from -0.15% <JUNO -$0.13> to -% <RENE.L -$11.26> in 12 equities;

·         Monday’s decliners ranged from -0.61% <CUR -$0.01> to -12,18% <CYTX -$0.047> in 32 equities;

·         Friday’s decliners ranged from -0.60% <NWBO -$0.002> to -7.82% <CUR -$0.14> in 31 equities;

·         Thursday’s decliners ranged from -0.11% <QURE -$0.02> to -8.5% <CAPR -$0.17> in 22 equities;

·         Last Wednesday’s decliners ranged from -0.18% <BLFS -$0.01> to -25.85% <BLCM -$2.12> in 27 equities;


… Look at the percentage’s (%) and spreads …

·         Wednesday’s gainers ranged from +0.17% <CLLS +$0.05> to +12.47% <SGMO +$2.45> in 25 equities;

·         Tuesday’s gainers ranged from +0.37% <PSTI +$0.01> to +8.41% <XON +$1.01> in 25 equities;

·         Monday’s gainers ranged from +0.02% <JUNO +$0.02> to +1.65% <NWBO +$0.0055> in 5 equities;

·         Friday’s gainers ranged from +0.04% <JUNO +$0.03> to +4.37% <CAPR +$0.08> in 7 equities;

·         Thursday’s gainers ranged from +0.17% <BLUE +$0.35> to +5.84% <VCEL +$0.45> in 15 equities;

·         Last Wednesday’s gainers ranged from +0.08% <JUNO +$0.07> to +7.94% <NWBO +$0.03> in 12 equities;


Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.