July 26, 2018 5:08pm

The opening throw was down, the first hour flipped to the upside reversing to the downside at the mid-day and closed negative of my 45 covered companies

Gene editing stocks, the continuous downward saga: getting “flushed” in another session… CRSP (-$1.05 or -2.07%), EDIT (-$0.28 or -0.88%) and NTLA (-$0.68 or -2.41%). There is still a LOT of historical upside to capitalize and SELL into!  My biggest question is where is the IR/PR response?

 

Pre-open indications: 5 hits and 3 miss (1 by $0.01)

 

I say today what others won’t, so you can do what others can’t!

Never leave an investor uninformed!  Want to know WHY, WHAT and HOW, 

Henry’omics:

 

The major stock indexes traded in different directions on Thursday as investors grappled with a disastrous quarterly report from Facebook (FB)

Nature Biotechnology had warned that CRISPR-Cas9 can lead to undesired “on target” deletions and rearrangements at the site of the gene of interest.

“It is important that anyone thinking of using this technology for gene therapy proceeds with caution and looks very carefully to check for possible harmful effects,” stated Allan Bradley, the study’s senior author.

  • We are listening but, where is the company’s response?

 

The advance/decline line scenario of 45 covered companies:   

  • The open was negative with an A/DL of 15/25 and 5 flats;
  • The first hour flipped positive with and A/DL of 28/14 and 3 flats;
  • The mid-day fell negative with an A/DL of 14/28 and 3 flats;
  • The close was negative with an A/DL of 14/26 and 5 flat;

 

Pre-open to close indications: 5 hit and 3 miss

  • bluebird bio (BLUE) closed down -$3.30 – hit;
  • CRISPR Therapeutics (CSP) closed down -$1.05 – hit;
  • Editas Medicine (EDIT) closed down -$0.28 – hit;
  • Intellia Therapeutics (NTLA) closed down -$0.68 – hit;
  • Fate Therapeutics (FATE) closed down -$0.01 – miss;
  • Pluristem (PSATI) closed down - $0.02 – miss – just can’t get any respect even with a real patent award;
  • Sage Therapeutics (SAGE) closed down -$3.45 – hit;
  • Solid Biosciences (SLDB) closed up +$0.86 – miss;

 

Of the 45 companies covered on Thursday; 26 downside equities finished in a range of -$0.03 (HSGX) to -$4.69 (SAGE) while the 14 upside equities oscillated from +$0.0 () to $8.85 () with 5 flat closes.

 

 

From the pre-open newsletter titled, “call as you may after FANGs get bumped. Are we set to stand tall or fall?  Biotech could be a safe corner for quiet time.”

I also stated, “A day of watch your stocks, keep your hands off some buttons and wait for most equities to find their balance.”                                                                                                 

 

Review gene editing pricings: Gene editing stocks are a game of pick-up-stick’s trading targets … https://www.regmedinvestors.com/articles/10412

 

Thursday: CRSP (-$1.05 or -2.07%), EDIT (-$0.28 or -0.82%) and NTLA (-$0.68 or -2.41%). The title says it all …

Wednesday: CRSPR stocks stayed in the downside for yet another session… CRSP (-$0.99 or -1.91%), EDIT (-$0.64 or -1.97%) and NTLA (-$0.28 or -0.98%). As I had stated in the mid-day, “Have “bottoms” been declared – not in their current DNA? Maintaining SELL as there is more historical upside to ‘eat’ through.”

Tuesday: CRSPR stocks stayed in the tank in yet another session… CRSP (-$5.46 or -9.53%), EDIT (-$2.91 or -8.23%) and NTLA (-$1.96 or -6.44%).

Monday: the hits just kept coming as the gene “editors” downside drift continues:  CRISPR Therapeutics (CRSP -$1.08 or -1.85%); Editas Medicine (EDIT -$0.88 or -2.23%) and Intellia Therapeutics (NTLA -$1.17 or -3.70;

Friday: follow the bouncing share pricing, a session of speculation to the downside: CRISPR Therapeutics (CRSP -$0.04 or +0.07%); Editas Medicine (EDIT +$0.12 or +0.33%) and Intellia Therapeutics (NTLA -$0.01 or -0.03%) …

Last Thursday: CRISPR Therapeutics (CRSP +$0.21 or +0.36%) stayed down for the count; Editas Medicine (EDIT +$0.75 or +2.12%) and Intellia Therapeutics (NTLA +$0.63 or +2.03%) …

The previous Wednesday: Editas Medicine (EDIT -$1.08 or -2.96%), CRISPR Therapeutics (CRSP -$3.48 or -5.61%) and Intellia Therapeutics (NTLA -$0.36 or -1.15%) …

The previous Tuesday, gene editing stocks high jumped in response to their dramatic decline: Editas Medicine (EDIT +$1.26 or +3.58%), CRISPR Therapeutics (CRSP +$1.95 or +3.25%) and Intellia Therapeutics (NTLA +$2.00 or +6.81%) …

The previous Monday, gene editing stocks dropped like stones in a lake: Editas Medicine (EDIT -$2.70 or -7.21%), CRISPR Therapeutics AG (CRSP -$5.65 or -8.60%) and Intellia Therapeutics (NTLA -$3.24 or -9.94%).

 

MY working trend (5 largest) lines:

… The greatest volume to the downside:  SGMO, CRSP, EDIT, BLUE and ONVO

… Upside volume was weighted to:  MDXG, XON, VSTM, BTX and ALNY

… Biggest $ downside: BLUE (-$3.65), SAGE (-$3.43), RGNX (-$2.10), ONCE (-$2.10) and AXGN (-$1.35)

 … Best moves to the $ upside: SLDB (+$0.91), ALNY (+$0.85), XON (+$0.73), BLFS (+$0.50) and MDXG (+$0.48)

… Flats:  AGTC, BTX, OSIR, RENE.L, STML

 

The weekly count - decliners versus gainers – looks at the view from different angles:

……. look at the differences in decliners:

  • Thursday’s decliners ranged from -0.11% <FATE -$0.01 > to -6.87% < HSGX -$0.16 > in 28 equities;
  • Wednesday’s decliners ranged from -0.06% < ONCE -$0.05> to -13.51% <BSTG -$0.52 > in 16 equities;
  • Tuesday’s decliners ranged from -0.22% <KOOL -$0.009 > to -10.44% <FATE -$1.14 > in 40 equities;
  • Monday’s decliners ranged from -0.21% <SAGE -$0.36 > to -6.82% <SLDB -$2.94 > in xx equities;
  • Friday’s decliners ranged from -0.03% <NTLA (-$0.01 > to -6.97% < MDXG -$0.28> in 24 equities;
  • Last Thursday’s decliners ranged from -0.24% < CRSP -$0.14> to -3.83% <ONCE -$3.27 > in 14 equities;

Versus

… Look at the percentage’s (%) and spreads …

  • Thursday’s gainers ranged from +0.10% <BMRN +$0.10 > to +10.85% <MDXG +$0.47> in 14 equities;
  • Wednesday’s gainers ranged from +0.23% <BCLI +$0.01 > to +9.62% <MDXG +$0.38 > in 24 equities;
  • Tuesday’s gainers ranged from +1.71% <IONS +$0.76 > to +4.40% < BCLI +$0.18> in 4 equities;
  • Monday’s gainers ranged from +0.46% <FATE +$0.05 > to +18.8% <CUR +$0.22> in 18 equities;
  • Friday’s gainers ranged from +0.10% <OSIR +$0.01 > to +4.12% <BLFS +$0.87 > in 15 equities;
  • Last Thursday’s gainers ranged from +0.18% <BMRN +$0.18 > to +21.68% <BSTG +$0.70 > in 30 equities;

 

Daily analytics and metrics:

  • The DOW closed up +112.97 or +0.44% to 25,527.07
  • The S&P closed down -8.63 points or -0.30% to 2,837.44
  • The NASDAQ closed down -80.05 points or -1.01% to 7,852.19

 

The CBOE Volatility Index (VIX) widely considered the best gauge of fear in the market:

  • Thursday traded at 12.14, down – 1.22%
  • Wednesday traded at 12.29, down -0.12%
  • Tuesday traded at 12.41, down -1.66%
  • Monday traded at 12.62, down -1.87%
  • Friday traded at 12.83, down -0.31%
  • Last Thursday traded at 12.87, up +6.36%

 

The iShares Russell 2000 (IWM) closed:

  • Thursday was up +0.51%;
  • Wednesday was up +0.37%;
  • Tuesday was down -1.06%;
  • Monday was up +0.12%;
  • Friday was down -0.42%;
  • Last Thursday was up +0.68%;

 

The iShares NASDAQ Biotechnology (IBB) closed:

  • Thursday was down -1.24%
  • Wednesday was up +1.11%
  • Tuesday was down -0.14%
  • Monday was down -0.06 %
  • Friday was down -0.08%
  • Last Thursday was up +0.10%

 

JULY sessions:

Thursday closed NEGATIVE with 26 decliners, 14 advancers and 5 flat;

Wednesday closed POSITIVE with 16 decliners, 24 advancers and 5 flat;

Tuesday closed NEGATIVE with 40 decliners, 4 advancers and 1 flat;

Monday (7/23) closed NEGATIVE with 25 decliners, 18 advancers and 2 flats;

Friday closed NEGATIVE with 24 decliners, 15 advancers and 5 flats;

Thursday closed POSITIVE with 14 decliners, 28 advancers and 2 flats;

Wednesday closed NEGATIVE with 30 decliners, 13 advancers and 2 flat;

Tuesday closed POSITIVE with 13 decliners, 29 advancers and 3 flat;

Monday (7/16) closed NEGATIVE with 32 decliners, 10 advancers and 3 flat;

Friday closed POSITIVE with 17 decliners, 25 advancers and 3 flat;

Thursday closed POSITIVE with 19 decliners, 24 advancers and 2 flat;

Wednesday closed POSITIVE with 18 decliners, 24 advancers and 3 flat;

Tuesday closed NEGATIVE with 29 decliners, 15 advancers and 1 flat;

Monday (7/9) closed POSITIVE with 18 decliners, 22 advancers and 5 flat;

Friday closed POSITIVE with 8 decliners, 35 advancers and 2 flat;

Thursday closed POSITIVE with 18 decliners, 23 advancers and 4 flat;

Wednesday (7/4) was a holiday;

Tuesday closed POSITIVE with 9 decliners, 33 advancers and 3 flat;

Monday (7/2) closed POSITIVE with 15 decliners, 27 advancers and 3 flat;

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.