December 24, 2019 2:25pm

Trading was subdued yet, the sector warmed-up with a Santa Claus rally

News: BioMarin Pharmaceutical (BMRN +$0.37) has submitted a biologics license application (BLA) to the FDA seeking approval for valoctocogene roxaparvovec, an investigational gene therapy, developed for treating adult patients with severe hemophilia A. BMRN anticipates that the review of the BLA will be initiated by the regulatory authority in February 2020.

Pre-open indications: 4 HITs <RENE.L (-$1.00); sold into strength: GBT (+$1.04), STML (+$0.31) and QURE (+$1.84)> 0 MISS >

Happy Hanukkah and a soon to be Christmas


 

May your holidays be rewarding by forgetting the market for a day or  two; also be safe if traveling and open to new motivation for portfolio return from RMi

 

The Dow closed down -36.08 points (-0.13%), the S&P closed down -0.63 points (-0.2%) and the NASDAQ closed UP +7.24 points (+0.08%)

 

The iShares NASDAQ Biotechnology (IBB) and the SPDR S&P ETF (XBI) indicators:

  • Tuesday the IBB closed up +0.58% while and XBI closed up +0.75%
  • Monday the IBB closed up +0.87% while and XBI closed up +1.01%
  • Friday the IBB closed up +0.90% and the XBI closed up +0.27%

 

The advance/decline line scenario of 45 covered companies:

  • Tuesday the close was positive with an A/D line of xx/x, x flat, 2 reversed merged (HSGX & ONVO), 2 dropped (BTX and CUR) and 3 acquired (ONCE, AST & OSIR);
  • Monday the close was positive with an A/D line of 33/5, 1 flat, 2 reversed merged (HSGX & ONVO), 2 dropped (BTX and CUR) and 3 acquired (ONCE, AST & OSIR);
  • Friday the close was negative with an A/D line of 15/19, 3 flats, 2 reversed merged (HSGX & ONVO), 2 dropped (BTX and CUR) and 3 acquired (ONCE, AST & OSIR);

 

Henry’omics:

The S&P 500 was flat as the NASDAQ fringed higher to another new record in muted Christmas Eve trading.

Pointing out a winner for three (3) sessions in a row – Applied Genetic Technologies (AGTC +$0.94 or +23.98% to $4.86) while followed by Sage Therapeutics (SAGE +$2.16), uniQure NV (QURE +$1.78) and Global Blood Therapeutics (GBT +$1.04)

From this a.m.’s post, “a shortened session; trading is expected to be subdued ahead of the Christmas holiday on Wednesday.”

Tuesday marked the official start of the Santa Claus rally period, which happened on the final five trading days of the year and the first two trading days of the New Year (2019).

Stocks tend to have unusually strong performance during those trading days with the S&P 500 averaging a 1.3% gain since 1950, according to the Stock Trader’s Almanac <CNBC>.

 

Don’t have … unrealistic and optimistic expectations about inflections in share pricing in regard to momentum.

 

Decliners:

  • ReNeuron (RENE.L -$1.00 after Monday’s +$3.50);
  • CRISPR Therapeutics (CRSP (-$0.65 after Monday’s -$0.18 and Friday’s+$2.92);
  • Cellectis SA (CLLS -$0.52);
  • Fate Therapeutics (FATE -$0.48);
  • Ionis Pharmaceuticals (IONS -$0.24);

Incliners:

  • bluebird bio (BLUE +$5.44 after Monday’s -$2.54);
  • Sage Therapeutics (SAGE +$2.16);
  • uniQure NV (QURE +$1.78 after Monday’s +$2.47 and last  Friday’s -$0.63);
  • Global Blood Therapeutics (GBT +$1.04 after Monday’s +$3.36 and Friday’s +$1.060;
  • Applied Genetic Technologies (AGTC +$0.94);

 

The percentage (%) indicators:

  • Tuesday’s range of the 27 upside was +0.28% (MDXG) to +23.98% (AGTC) while the 10 downside ranged from -0.02% (BOLD) to -4.11% (CLBS); 
  • Monday’s range of the 32 upside was +0.14% (MDXG) to +11.22% (ADRO) while the 5 downside ranged from -0.08% BLUE) to -0.73% (SAGE); 
  • Friday’s range of the 15 upside was +0.06% (AXGN) to +29.83% (AGTC) while the 19 downside ranged from -0.16% (NTLA) to -4.01% (XON); 

 

Upside volume stats:  to compare

  • Tuesday: 5 out of the 27 upside had higher than the 3 month average volume;
  • Monday: 9 out of the 35 upside had higher than the 3 month average volume;
  • Friday: 9 out of the 15 upside had higher than the 3 month average volume;

Downside volume stats:

  • Tuesday: 2 out of the 10 downside had higher than the 3 month average volume;
  • Monday: 1 out of the 2 downside had higher than the 3 month average volume;
  • Friday: 12 out of the 19 downside had higher than the 3 month average volume;

 

1 flat –BSTG

 

December’s sessions:

Tuesday closed POSITIVE with 10 decliners, 27 advancers, 1 flat, 2 dropped (BTX & CUR) and 3 acquired (ONCE, AST & OSIR) and 2 reversed (HSGX & ONVO);

Monday closed POSITIVE with 2 decliners, 35 advancers, 1 flat, 2 dropped (BTX & CUR) and 3 acquired (ONCE, AST & OSIR) and 2 reversed (HSGX & ONVO);

Friday closed NEGATIVE with 19 decliners, 15 advancers, 3 flats, 2 dropped (BTX & CUR) and 3 acquired (ONCE, AST & OSIR) and 2 reversed (HSGX & ONVO);

Thursday closed POSITIVE with 12 decliners, 24 advancers, 2 flats, 2 dropped (BTX & CUR) and 3 acquired (ONCE, AST & OSIR) and 2 reversed (HSGX & ONVO);

Wednesday closed NEGATIVE with 23 decliners, 13 advancers, 3 flat, 2 dropped (BTX & CUR) and 2 acquired (AST & OSIR) and 2 reversed (HSGX & ONVO);

Tuesday closed NEGATIVE with 22 decliners, 16 advancers, 1 flat, 2 dropped (BTX & CUR) and 2 acquired (AST & OSIR) and 2 reversed (HSGX & ONVO);

Monday closed POSITIVE with 13 decliners, 25 advancers, 1 flat, 2 dropped (BTX & CUR) and 2 acquired (AST & OSIR) and 2 reversed (HSGX & ONVO);

Friday closed NEGATIVE with 24 decliners, 16 advancers, 1 flat, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Thursday closed POSITIVE with 14 decliners, 27 advancers, 0 flat, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Wednesday closed NEGATIVE with 13 decliners, 27 advancers, 1 flat, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Tuesday closed POSITIVE with 17 decliners, 22 advancers, 2 flats, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Monday closed NEGATIVE with 31 decliners, 9 advancers, 1 flat, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Friday closed POSITIVE with 9 decliners, 29 advancers, 3 flats, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Thursday closed NEGATIVE with 31 decliners, 9 advancers, 1 flat, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Wednesday closed POSITIVE with 13 decliners, 25 advancers, 4 flats, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Tuesday closed POSITIVE with 12 decliners, 25 advancers, 4 flats, 1 dropped (BTX) and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

Monday closed NEGATIVE with 26 decliners, 19 advancers, 2 flats and 2 acquired (AST & OSIR) and 1 reversed (HSGX);

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.