November 13, 2020 6:07pm

A weekly boost from vaccine news amid a rising number of coronavirus cases and the Fed’s uncertain economic outlook

Pre-open indication results: 4 HITs and 3 MISS

Week in review …

An “intelligence newspaper” for smart investing in the RegMed, gene and cell therapy sector.  I track the numbers, so there’s no question re my opinion; so, you can do what others can't.

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The Dow closed UP +399.64 points (+1.37%), the S&P closed UP +48.14 points (+1.36%) while the Nasdaq closed UP +119.70 points (+1.02%)

 

Henry’omics:

Indexes rose on Friday as investors optimism benefits from a potential effective vaccine.

The Dow rose 4.1% for the week, the S&P 500 closed 2.16% higher as the Nasdaq lost 0.6% this (its third weekly loss in four weeks).

The Russell 2000, which tracks small-cap stocks, jumped more than 2% to an intraday record, and posted its first all-time closing high since August 2018.

 

Pre-open indication: 4 HITs < Precigen (PGEN -$0.13), Fate Therapeutics (FATE -$1.47), Editas Medicine (EDIT +$1.43), uniQure NV (QURE +$0.81) and 3 MISS < Biostage (BSTG -$0.045 with 1,010 shares traded), Global Blood Therapeutics (GBT +$2.88), Verastem (VSTM +$0.03)

 

This morning, I stated in this a.m.’s newsletter – RegMed Investors’ (RMi) pre-open: a Friday high as uncertainty reigns? https://www.regmedinvestors.com/articles/11634

 

RegMed/Cell and Gene therapy 35 covered equities’ Advance/Decline (A/D) lines: progressions and regressions …

  • Friday opened positive at 22/11 and 2 flats, stayed positive at the mid-day at 21/13 and 1 flat, closing positive at 22/11 and 1 flat;
  • Thursday opened positive at 17/14 and 4 flats, stayed positive at the mid-day at 18/16 and 1 flat, closing negative at 19/15 and 1 flat;
  • Wednesday opened negative at 13/19 and 3 flats, stayed negative at the mid-day at 16/17 and 2 flats, closing positive at 17/15 and 3 flats;
  • Tuesday opened negative at 13/17 and 5 flats, stayed negative at the mid-day at 9/923 and 3 flats, cruised positive at 3p.m. at 21/12 and 2 flats to close positive at 22/11 and 2 flats;
  • Monday opened positive at 25/7 and 3 flats, stayed positive at the mid-day at 24/9 and 2 flats, closing positive at 21/12 and 2 flats;

 

Key metrics:

  • Sector volume was the usual LOW with 4 of the 22-upside having higher than the 3-month average volume with the increased volume of 6 of 11-downside having higher than the 3-month average volume;
  • Friday’s percentage (%) of the 22-upside were +0.40% (FIXX) to +11.85% (NTLA) while the 11-downside ranges from -0.31% (SLDB) to -6.91% (ATHX);

 

Hammered in today’s market:

  • Fate Therapeutics (FATE), Adverum Biotechnologies (ADVM), Brainstorm Cell Therapeutics (BCLI), Applied Genetic Technologies (AGTC), Chinook Therapeutics (KDNY) to name 5 of the 11 declining of the 35 covered

Jumping with share pricing momentum:  

  • Intellia therapeutics (NTLA), Alnylam Pharmaceuticals (ALNY), Global Blood Therapeutics (GBT), Ionis Pharmaceuticals (IONS), CRISPR Therapeutics (CRSP), to name 5 of the 22 inclining of the 35 covered

 

The iShares NASDAQ Biotechnology (IBB) and the SPDR S&P ETF (XBI) indicators:

  • Friday, the IBB closed up +1.10% and XBI closed up +1.06%
  • Thursday, the IBB closed up +0.01% and XBI closed up +0.06%
  • Wednesday, the IBB closed up +1.29% and XBI closed up +1.39%
  • Tuesday, the IBB closed up +0.40% and XBI closed up +1.50%
  • Monday, the IBB closed down -0.08% and XBI closed up +0.42%

 

Friday’s (10 of 22) incliners:

  • Intellia therapeutics (NTLA +$3.52);
  • Alnylam Pharmaceuticals (ALNY +$3.07 after Thursday’s +$3.35, Wednesday’s +$3.20, Tuesday’s -$2.43 and Monday’s -$3.25);
  • Global Blood Therapeutics (GBT +$2.88 after Thursday’s +$2.58);
  • Ionis Pharmaceuticals (IONS +$2.32);
  • CRISPR Therapeutics (CRSP +$2.19 after Thursday’s +$1.13, Wednesday’s +$1.35, Tuesday’s -$0.95 and Monday’s -$3.01);
  • Ultragenyx (RARE +$1.74 after Thursday’s -$5.20, Wednesday’s +$2.35, Tuesday’s +$3.76 and Monday’s +$2.30);
  • Sage Therapeutics (SAGE +$1.52 after Thursday’s -$0.27, Wednesday’s -$1.27, Tuesday’s +$1.81 and Monday’s -$0.23);
  • Editas Medicine (EDIT +$1.43 after Thursday’s +$1.30, Wednesday’s -$0.78, Tuesday’s -$0.53 and Monday’s -$0.08);
  • Vericel (VCEL +$1.18);
  • Cellectis SA (CLLS +$1.13 after Thursday’s +$0.38, Wednesday’s +$0.23, Tuesday’s -$0.92 and Monday’s +$0.84);

Friday’s (11 of 11) decliner:

  • Fate Therapeutics (FATE -$1.47 after Thursday’s -$1.40, Wednesday’s +$0.31, Tuesday’s +$1.92 and Monday’s +$2.41);
  • Brainstorm Cell Therapeutics (BCLI -$0.78 after Thursday’s`+$0.46);
  • Adverum Biotechnologies (ADVM -$0.76);
  • Applied Genetic Technologies (AGTC -$0.19);
  • Chinook Therapeutics (KDNY -$0.13 after Thursday’s +$0.67);
  • Athersys (ATHX -$0.13);
  • Bellicum Pharmaceuticals (BLCM -$0.13);
  • Voyager therapeutics (VYGR -$0.08);
  • Pluristem (PSTI -$0.04 after Thursday’s +$0.14, Wednesday’s +$0.43, Tuesday’s -$0.04 and Monday’s -$1.13);
  • Precigen (PGEN -$0.02 after Thursday’s +$0.15, Wednesday’s -$0.22 and Tuesday’s +$0.57);
  • Solid Biosciences (SLDB -$0.01);

Closing 1 –Stemline Therapeutics (STML – acquired)

 

Percentage (%) movement/range statistics: a 360 degrees comparison of % and pricing

  • Friday’s percentage (%) of the 22-upside were +0.40% (FIXX) to +11.85% (NTLA) while the 11-downside ranges from -0.31% (SLDB) to -6.91% (ATHX);
  • Thursday’s percentage (%) of the 15-upside were +0.04% (ADVM) to +6.85% (GBT) while the 19-downside ranges from -0.15% (BLUE) to -5% (BSTG);
  • Wednesday’s percentage (%) of the 17-upside were +0.03% (AXGN) to +9% (BLCM) while the 15-downside ranges from -0.36% (VCEL) to -8.14% (AGTC);
  • Tuesday’s percentage (%) of the 22-upside were +0.16% (IONS) to +11.11% (BSTG with only 200 shares traded) while the 11-downside of -0.46% (PSTI) to -23.21% (VYGR);
  • Monday’s percentage (%) of the 21-upside were +0.35% (BCLI) to +17.68% (RENE.L) while the 12- downside of -0.26% (EDIT) to -15.62% (BSTG);

 

Sentiment and a few daily indicators:

Sentiment on Thursday soured even further after Fed Chair Powell said the country’s economic outlook remained uncertain. “With the virus spreading, the next few months could be challenging,” he said. <CNBC>

Infection cases <Million>:

  • Friday 10.56 M cases
  • Thursday 10.41 M cases
  • Wednesday 10.26 M cases
  • Tuesday 10.1 M cases
  • Monday 10 M cases

Friday’s death rate totaled 242,536 after Thursday’s 241,907, Wednesday’s 239,732, Tuesday’s 238,251, Monday’s 237,742 and last Friday’s 234,049 <Johns Hopkins University>

 

Stats:

Upside volume: 

  • Friday: 4 out of the 11-upside had higher than the 3-month average volume;
  • Thursday: 5 out of the 15-upside had higher than the 3-month average volume;
  • Wednesday: 4 out of the 17-upside had higher than the 3-month average volume;
  • Tuesday: 8 out of the 22-upside had higher than the 3-month average volume;
  • Monday: 15 out of the 21-upside had higher than the 3-month average volume;

The CBOE Volatility Index (VVIX: INDEX) tracked:

  • Friday was down -2.25 points or -8.88% at 23.10
  • Thursday was up +1.90 points or +8.10 % at 25.35
  • Wednesday was down -1.33 points or -5.36% at 23.47
  • Tuesday was down -0.95 points or -3.69% at 24.80
  • Monday was up +0.89points or +3.58% at 25.75

Downside volume:

  • Friday: 6 out of the 22-downside had higher than the 3-month average volume;
  • Thursday: 6 out of the 19-downside had higher than the 3-month average volume;
  • Wednesday: 4 out of the 15-downside had higher than the 3-month average volume;
  • Tuesday: 6 out of the 11-downside had higher than the 3-month average volume;
  • Monday: 6 out of the 12-downside had higher than the 3-month average volume;

 

November, the 2nd month of Q4 …

Friday closed positive with 22 advancers, 11 decliners and 1 flat 

Thursday closed negative with 15 advancers, 19 decliners and 1 flat 

Wednesday closed positive with 17 advancers, 15 decliners and 3 flats 

Tuesday closed positive with 22 advancers, 11 decliners and 2 flats 

Monday (11/9) closed positive with 21 advancers, 12 decliners and 2 flats 

Friday closed negative with 6 advancers, 28 decliners and 1 flat 

Thursday closed positive with 20 advancers, 11 decliners and 4 flats 

Wednesday closed positive with 28 advancers, 4 decliners and 3 flats  

Tuesday closed positive with 30 advancers, 4 decliners and 1 flat 

Monday (11/2) closed positive with 17 advancers, 15 decliners and 3 flats 

 

The Bottom Line: Friday, the 13th – exhibits a positive “vibe’ in the sector as the market drives momentum.

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.