September 10, 2021 7:39am

Pre-open indications: BUY: 3; Maintain SELL: 1

My version of the morning’s “indications” is about what you need to know; it’s what could happen or materialize after the opening and what might happen during the session

Framing the main takeaway … pricing, volume and trading creates volatility and liquidity!

Dow futures are UP +0.52% (+181 points), S&P futures are UP +0.43% (+20 point) and NASDAQ futures are UP +0.42% (+66 point)


U.S. stock index futures were higher in early morning trading on Friday,

European shares were guardedly higher

Asia-Pacific shares were higher as investors monitored Hong Kong-listed stocks of firms in regulation-hit sectors such as video games, Japan and Australia were also up.



During Thursday’s session, the Dow dived -151.69 points, or -0.43%, while the S&P slipped -20.79 points or -0.46%. It was the fourth (4th) consecutive day of losses for each while the Nasdaq dived -38.38 points or - 0.25% for its second (2nd) straight day of losses.

  • Despite Thursday’s losses the major averages are still hovering around their all-time highs. The Dow is roughly 2% below its record, while the Nasdaq and S&P are about 1% from theirs. <CNBC>
  • All three indices are on track to end the week in the red.

For the holiday-shortened week, the consumer discretionary sector is the best-performing S&P group, up about a quarter of one percent. The other ten sectors are all in the red. Industrial and real estate stocks are the biggest losers, with each sector down more than 2%. <CNBC>


If you didn’t remember what happen at Thursday night’s close and the quarter’s “number’s” impact, you won’t be prepared for today’s session:

  • The Nasdaq closed DOWN -38.38 points (-0.46%);
  • The IBB closed up +0.12% and XBI closed up +0.39%;
  • Sector volume was LOW with 5 of the 20-upside having higher than the 3-month average volume with very LOW volume of 2 of 13-downside having higher than the 3-month average volume;
  • The CBOE Volatility Index (VVIX: INDEX) was up +0.84 points or +4.68% at 18.80;
  • Thursday’s percentage (%) of the 20-upside were +0.19% (BLFS) to +19.88% (BSTG) while the 13-downside -0.29% (FATE) to -6.30% (MESO);


  • September, 3 positive and 3 negative close
  • August - 12 positive and 10 negative close
  • July: 6 positives, 1 holiday and 15 negative closes


Q2/21 Earnings releases …  … to date:


Companies in my headlights – It’s your decision; I provide an idea and context:

The Biostage (BSTG) Chronicles - Maintaining Sell – notice how the shares trade with the “pump/promote”?

Biostage (BSTG) closed up again Thursday +$0.66 to $3.98 with 6,062 shares traded after Wednesday’s +$0.57 to $3.32 with 7,833 shares traded after Tuesday’s -$0.75 to $2.75 with 6,705 shares traded following Monday’s Holiday

Question#1: Being able to trade a stock doesn't mean it is worth the share price; an equity that has WHAT is BSTG’s value proposition, after all the share price pumping – NO clinical trial after a 1.5-year-old IND?

Questiob#2: WHAT is the end game of “pumping” the share price as the float is MINIMAL compared to the ever-OUTSTANDING shares? 

MINORITY PUBLIC shareholders are waiting for the specific time, watching and weighing responses to MAINTAIN their RIGHTS.


Pre-open Indications:  who and what’s lookin’ which way …


Intellia Therapeutics (NTLA) closed up +$0.02 Thursday after Wednesday’s -$3.36 after being down Tuesday -$13.53 to $163.25 and last Friday’s up again +$2.77 to $176.78 with a positive +$2.13 or +1.32% pre-market indication,

CRISPR Therapeutics (CRSP) closed up Thursday +$2.20 after Wednesday’s -$1.25 after being down again -$1.45 to $120.51 following last Friday’s -$5.11 to $121.96 and has a positive +$1.54 or +1.27% pre-market indication,

Editas Medicine (EDIT) closed up +$0.13 on Thursday after Wednesday’s -$2.41, Tuesday’s -$1.52 to $66.73 and last Friday’s -$4.69 and has a positive +$2.34 or +3.36% pre-market indication,


The BOTTOM LINE: It’s Friday and some want to “skim” some profits but, they’re not that high after a week of falling share pricing.

Sector sentiment has been more than light on Thursday yet was almost non-existent on Wednesday and Tuesday (after Monday’s holiday) following last Friday’s negative closes.

When you’re on a roller coaster, the only thing you can be sure of is you’ll end up back where you started

Investors should take short-term profits to cash-up for coming drifts!

Some earnings’ Reports Outstanding:

  • Applied Genetic Technologies (AGTC), Mesoblast (MESO) – still trying to access, Pluristem (PSTI) and ReNeuron (RENE.L)

RMi’s daily report is a primer that may say little or a lot; yet it serves as insurance that all indications are being examined and evaluated.


Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Regulation Analyst Certification ("Reg AC"): The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and its or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed in this report.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.