May 2, 2025 8:07am

Weak seasonal trends exacerbates as we head into “Sell in May” that could hit harder this month before the slog could also hit hardest in June

Futures rise as China signals openness to trade talks

Breaking: The US economy added 177,000 nonfarm payrolls in April, more than the 138,000 expected by economists. The unemployment rate held steady at 4.2%. Average hourly earnings in April rose 0.2% over last month and 3.8% over the prior year. Economists expected wages to rise 0.3% over last month and 3.9% over the prior year. With a notable jump in hiring in the transportation and warehousing sector, which saw 29,000 jobs crated, up from a more modest 2,700 in March. Federal government employment, which has been closely watched given the Trump administration's DOGE initiatives, fell by 9,000. Total government employment, which includes state and local hiring, rose by 10,000 last month.

6 earnings released, 4 new LPS (loss-per-shares) and 2 net income (MDXG)

No false narratives or fake news; to read insights and analysis on the latest sector action, check out Pre-Open Brief

Never leave an investor uninformed!

Remember that overnight and pre-open actions’ futures and markets doesn’t necessarily translate into actual trading in today’s market session.

“I also hate to be so negative or contrarian but, this is a NO spin zone and truth is its product; I can always be WRONG but, I am mostly EARLY!”

My interpretation of the morning’s numbers is written to be informative; it’s built on what happened to make “it” happen today!

 

Thursday’s night’s … RegMed Investors (RMi) Closing Bell: earnings lift the veil, there’s “meat on the bones” … https://www.regmedinvestors.com/articles/13902

RegMed Investors (RMi) Research Note: Harvard Apparatus GT (OTCQB: HRGN), The latest, WHAT happens to OTCQB: HRGN if the White House and the new head of the SEC starts to "DELIST" Chinese companies??? … Newest happening, public accountants walk … https://www.regmedinvestors.com/articles/13812

 

Friday: The pre-open Dow futures are UP +0.89% or (+365 points), the S&P futures are UP +1.01% or (+56 points) and the Nasdaq futures are UP +0.99% or (+196 points)

  • Futures add to index add a more positive upside, Friday - 5/2,
  • European stocks were higher,
  • Asia-Pacific markets rise as China evaluates possibility of trade talks with the U.S.

 

Henry’omics: We need to more than consider the economic environment to comprehend the micro re “our” universe of cell and gene therapy companies

Thursday: The Dow closed UP +83.42 points or +0.21%, the S&P closed UP +35.05 points or +0.63% while the Nasdaq closed UP +264.40 points or +1.52%

Wednesday: The Dow closed UP +141.74 points or +0.35%, the S&P closed UP +8.23 points or +0.15% while the Nasdaq closed DOWN -14.98 points or -0.09%

Tuesday: The Dow closed UP +300.03 points or +0.75%, the S&P closed UP +32.04 points or +0.58% while the Nasdaq closed UP +95.18 points or +0.55%

Monday: The Dow closed UP +114.09 points or +0.28%, the S&P closed UP +3.54 points or +0.06% while the Nasdaq closed DOWN -16.81 points or -0.10%

Economic Data Docket: April jobs report

  • Economists expect nonfarm payroll to have risen by 135,000 in April while the unemployment rate held steady at 4.2%, according to consensus estimates <Bloomberg>
  • The payrolls report is the latest in a blast of economic data this week, with a gross domestic product reading that showed the economy contracted 0.3% at an annualized pace in the first quarter. Private payrolls data from ADP also came in weak, and the latest weekly jobless claims ballooned to 241,000, higher than expected. <CNBC>

 

Q2 – May – 1 negative close

  • Q2 - April – 10 negative and 11 positive closes

Q1/25

  • March, 10 positive and 11 negative closes
  • February – 12 holiday, 11 negative and 7 positive closes
  • January - 2 holidays, 1 market close, 10 negative and 10 positive closes

 

Companies in my headlights – It’s your decision; I provide ideas and context

I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths.  A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.

  • Better part of valor to not lead any investor to temptation; yet again, I am passing on forecasting the daily indications as to expectation while the aftermarket blanked while the pre-open waits for the …  econs, it is still a mix of ups, downs and just uncertainty

 

The BOTTOM LINE: Cell and gene Therapy sector equities stocks, 2nd session evolves afte diving on the 1st session of may after finishing April and ending in a positive close.

  • Wild swings will continue
  • The last week of April and Q1; Tuesday and Monday closed negative …

Last week, the cell and gene therapy sector dived on Friday after bounding on Thursday, Wednesday, Tuesday and Monday.

May ‘25: understand the “flow” of bad market and economic karma…

  • 5/1 – Thursday closed negative with 14 positive, 19 negative and 2 flats

Last 2 weeks of April:

  • 4/30 - Wednesday closed positive with 23 positive, 10 negative and 2 flats
  • 4/29 – Tuesday closed negative with 14 positive, 20 negative and 1 flat
  • 4/28 - Monday closed negative with 15 positive, 19 negative and 2 flats
  • 4/25 – Friday closed negative with 12 positive, 20 negative and 3 flats
  • 4/24 – Thursday closed positive with 29 positive, 5 negative and 1 flat
  • 4/23 – Wednesday closed positive with 22 positive, 10 negative and 3 flats
  • 4/22 – Tuesday closed positive with 30 positive, 3 negative and 2 flats
  • 4/21 - Monday closed positive with 21 positive, 13 negative and 1 flat

Brace ourself for more economics and their down trending affect?

 

Welcome to my world of defining the “grey’ in our universe!

  • The sector is what it is, until it isn’t and even then, it doesn’t seem to be… as NOT much changes as the sector’s share pricing rides the waves of volatility, algorithms, electronic trading and short covering.
  • I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.  Regulation Analyst Certification (Reg AC): The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and it’s or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed in this report.

Henry McCusker, the editor and publisher of RegMed Investors could hold or have positions securities referred to in this publication and he will NOTIFY investors of holdings.