October 3, 2025 8:15am

Data blackout removes a factor that could lend pressure to stocks

Markets have so far been unperturbed by the government shutdown, which looks set to drag on; although 7 positive sector closes of the last 9 sessions could set a trap for “some” profiteering

Pre-open Signals: 5 Positive Indications

Never leave an investor uninformed … I say what others won’t, so you can do what others can’t!

TGIF

As a quantamental “plotter” I equate myself to a quantitative analyst straddling fundamental stock picking to produce better results for investors. the term “quantamental,” blends styles setting forth my difference re: retail, trading and multiple investor categories

Remember that overnight and pre-open actions’ futures and markets doesn’t necessarily translate into actual trading in today’s market session.

 

Wednesday night’s … RMi Closing Bell: Resilience … https://www.regmedinvestors.com/articles/14132

 

Friday: The pre-open Dow futures are UP +0.16% or (+77 points), the S&P futures are UP +0.12% or (+8 points) and the Nasdaq futures are UP +0.14% or (+35 points)

  • Stock futures rose minimally Friday, 10/3
  • European stocks inched higher,
  • Asia-Pacific markets traded mixed

 

Henry’omics: We need to more than consider the markets …environment to comprehend the micro re “our” universe of cell and gene therapy companies

  • Thursday: The Dow closed UP +78.62 points or +0.17%, the S&P closed UP +4.15 points or +0.06% while the Nasdaq closed UP +88.894 points or +0.39%
  • Wednesday: The Dow closed UP +43.21 points or +0.09%, the S&P closed UP +22.74 points or +0.34% while the Nasdaq closed UP +95.148 points or +0.422%
  • Tuesday: The Dow closed UP +81.82 points or +0.18%, the S&P closed UP +27.25 points or +0.41% while the Nasdaq closed UP +68.855 points or +0.31%
  • Monday: The Dow closed UP +68.78 points or +0.15%, the S&P closed UP +17.51 points or +0.26% while the Nasdaq closed UP +107.085 points or +0.48%
  • Last week, the Dow has shed 0.8%, the S&P 500 is down nearly 0.9% and the Nasdaq has lost about 1.1%
  • Last month and Q3’s numbers, the S&P 500 Q is up 7% and the month -4.2%, the Nasdaq’s Q is up +11% and the month +5% while the Dow’s Q is up +5% and the month +1%

Economic Data Docket: delayed

 

Q4 – 2 positive closes

  • Q3 – September, 1 holiday, 9 negative and 12 positive closes; August - 11 negative and 9 positive closes; July – 1 market holiday, 13 positive and 9 negative closes

 

Companies in my headlights – It’s your decision; I provide ideas and context

I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths.  A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.

  • October begins with a government shutdown and fewer econs… along with the usual ups, downs and just plain uncertainties

Some indications in MY view:

CRISPR Therapeutics (CRSP +$6.66 after Wednesday’s +$1.35, Tuesday’s +$1.04 and Monday’s +$2.10 with a positive +$0.58 or +0.80% pre-open

Beam Therapeutics (BEAM) closed up +$1.46 after Wednesday’s -$0.14 with a positive +$0.31 or +1.21% pre-open

BioNTech (BNTX +$2.30 after Wednesday’s +$3.59 and Tuesday’s +$0.52 with a positive +$0.04 or +0.04% pre-open

Ionis Pharmaceuticals (IONS) closed up +$2.60 with a positive +$0.30 or +0.44% pre-open

Ultragenyx Pharmaceuticals (RARE +$0.91 after Wednesday’s -$0.09, Tuesday’s -$0.28 and Monday’s +$1.28 with a positive +$0.04 or +0.16%

 

The BOTTOM LINE: I can’t seem to let go of this quote, “It’s always darkest before the pitch dark”

  • The cell and gene therapy sector ended seeing a few too many fits and starts, so …

Reiterating, “What to Do Now: The stock market rally continues to do well, but … with the major indexes all near record highs … “uncle algo and his electronic trading dwarfs” are smelling some profits!”

Welcome to my world of defining the “grey’ in our universe!

  • I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.

 

October: understand the new “flow” …

  • 10/2 – Thursday closed positive with 26 positive, 13 negative and 1 flat
  • 10/1 – Wednesday closed positive with 26 positive, 14 negative and 0 flat
  • 9/30 -Tuesday closed positive with 24 positive, 15begative and 1 flat,
  • 9/29 – Monday closed positive with 33 positive, 5 negative and 2 flats

Last week:

  • 9/26 – Friday closed positive with 29 positive, 9 negative and 2 flats
  • 9/25 - Thursday closed negative with 8 positive, 30 negative and 2 flat
  • 9/24 – Wednesday closed positive with 28 positive, 11 negative and 1 flat
  • 9/23 – Tuesday closed negative with 7 positive, 32 negative and 1 flat
  • 9/22 – Monday closed positive with 31 positive, 9 negative and 0 flat

 

Q3 Earnings are in the front-view mirror; we are about to start again …!

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.  Regulation Analyst Certification (Reg AC):

The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and it’s or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed.