October 7, 2025 8:13am

Keep your wallet in the draw!

The major indexes are near record highs; “Uncle algo and his electronic trading dwarfs” are STILL smelling some profits! With my usual mantra, “When indexes go this high, I say … BYE”

Pre-open Signals: 2 Positive Indications

Never leave an investor uninformed … I say what others won’t, so you can do what others can’t!

U.S. stock futures were noodling Tuesday, with investors opting to take some profit following 7 straight days of gains for the benchmark S&P 500. S&P 500 futures and contracts tied to the Nasdaq 100 were also each down 0.1%, after the gauges each notched record closing highs on Monday.

Remember that overnight and pre-open actions’ futures and markets doesn’t necessarily translate into actual trading in today’s market session.

Monday night’s … RMi Closing Bell: Red is the color of the session … https://www.regmedinvestors.com/articles/14138

 

Monday: The pre-open Dow futures are UP +0.03% or (+16 points), the S&P futures are UP +0.03% or (+2 points) and the Nasdaq futures are UP +0.10% or (+26 points)

  • Futures are positive and still fluctuating minimally on Tuesday, 10/7
  • European stocks were higher on Tuesday afternoon,
  • Asia Pacific markets were mixed with Chinese, Hong Kong and South Korean markets closed for the holidays.

 

Henry’omics: We need to more than consider the markets …environment to comprehend the micro re “our” universe of cell and gene therapy companies

  • Monday: The Dow closed DOWN -63.31 points or -0.14%, the S&P closed UP +24.49 points or +0.36% while the Nasdaq closed UP +161.161 points or +0.71%
  • Friday: The Dow closed UP +238.56 points or +0.51%, the S&P closed UP +0.44 points or +0.01% while the Nasdaq closed DOWN -63.545 points or -0.28%
  • Last week, the Dow was up +1.3%, the S&P 500 is +1.1% and the Nasdaq has lost about 1.3%
  • Last month and Q3’s numbers, the S&P 500 Q was up +7% and the month -4.2%, the Nasdaq’s Q is up +11% and the month +5% while the Dow’s Q is up +5% and the month +1%

Economic Data Docket: None

 

Q4 – 3 positive and 1 negative closes

  • Q3 – September, 1 holiday, 9 negative and 12 positive closes; August - 11 negative and 9 positive closes; July – 1 market holiday, 13 positive and 9 negative closes

 

Companies in my headlights – It’s your decision; I provide ideas and context

I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths.  A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.

  • October begins with a government shutdown and fewer econs… along with the usual ups, downs and just plain uncertainties

Some indications in MY view:

Arrowhead Pharmaceuticals (ARWR +$1.38 after Friday’s +$1.52 with a positive +$1.45 or +3.87% pre-open

Beam Therapeutics (BEAM +$0.14 with a positive +$0.17 or +0.66% pre-open

 

The BOTTOM LINE: I can’t seem to let go of this quote, “It’s always darkest before the pitch dark”

  • The S&P 500 closed at a fresh record for the 32nd time this year, up for 7 straight days, while the Nasdaq notched its 31st all-time high of 2025. The Dow ended the day lower, however. The Russell 2000 (RUT) index of small-capitalization stocks finished the previous session at a record high after crossing 2,500 for the 1st time.

Reiterating, “What to Do Now: The stock market with the major indexes all near record highs … “uncle algo and his electronic trading dwarfs” are smelling some FURTHER profits!”

 

Welcome to my world of defining the “grey’ in our universe!

  • I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.

 

October: understand the new “flow” …

This week:

  • 10/6 – Monday closed negative with 17 positive, 22 negative and 1 flat

Last week:

  • 10/3 – Friday closed positive with 27 positive, 10 negative and 3 flats
  • 10/2 – Thursday closed positive with 26 positive, 13 negative and 1 flat
  • 10/1 – Wednesday closed positive with 26 positive, 14 negative and 0 flat
  • 9/30 -- Tuesday closed positive with 24 positive, 15 negative and 1 flat
  • 9/29 – Monday closed positive with 33 positive, 5 negative and 2 flats

The previous week:

  • 9/26 – Friday closed positive with 29 positive, 9 negative and 2 flats
  • 9/25 - Thursday closed negative with 8 positive, 30 negative and 2 flat
  • 9/24 – Wednesday closed positive with 28 positive, 11 negative and 1 flat
  • 9/23 – Tuesday closed negative with 7 positive, 32 negative and 1 flat
  • 9/22 – Monday closed positive with 31 positive, 9 negative and 0 flat

 

Q3 Earnings are in the front-view mirror; we are about to start again …!

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.  Regulation Analyst Certification (Reg AC):

The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and it’s or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed.