January 5, 2026 7:53am

The fact of 2 things “being seen or placed close together” after Friday’s barely positive close in the 1st session of 2026 post multiple negative sessions

Let’s not forget, some serious econ releases this week and geopolitics uncertainties

Pre-open Signals: 2 Negative; If you understand probabilities, the inevitable is easier to maneuver

Never leave retail investor uninformed … I say what others won’t, so you can do what others can’t!

 

No Don Quixote as I continually ask, what do all these stock sources, I-Banks and brokers do for you in providing daily information? Availability of data have made intel both complex; I see myself as a collector and my responsibility is to further identify and interpret data to bridge some gaps in an investment decision.

 

RMi Closing Bell: Flickering unsteadily … https://www.regmedinvestors.com/articles/14252

RMi Research Note: Capricor Therapeutics (CAPR) DUMP before the next big SLUMP! … https://www.regmedinvestors.com/articles/14249

RMi Research Note: Harvard Apparatus GT (OTCQB: HRGN): I reiterate WHO is pumping the volume and share pricing? … https://www.regmedinvestors.com/articles/13812   

 

I make a commitment to provide need-to-know “facts in evidence” as an equity’s volatility is one tactical signal for stocks. My thesis is important in trying to distinguish the temporary from real pricing digression or progress.

 

Monday (1/2): The pre-open Dow futures are DOWN -0.02% or (-10 points), the S&P futures are UP +0.27% or (+18 points) and the Nasdaq futures are UP +0.65% or (+166 points)

  • U.S. stock futures are on the rise, Monday 1/5/26,
  • European markets traded higher,
  • Asia Pacific markets traded to a record high.

 

Economic Data:  ISM Manufacturing Index and Auto sales

  • On Friday, the December jobs report is expected to show a slowdown in hiring in the final month of 2025, with economists expecting nonfarm payrolls to grow by 55,000, down from November's job gains of 64,000. The unemployment rate, which hit a four-year high of 4.6% in November, is expected to fall by 0.1%.

 

Henry’omics: We need to more than consider the market’s setting to grasp the micro re “our” universe of cell and gene therapy companies

  • Friday: The Dow closed UP +319.10 points or +0.66%, the S&P closed UP +12.97 points or +0.19% while the Nasdaq closed DOWN -6.362 points or -0.03%
  • Thursday was New Year’s holiday
  • Wednesday: The Dow closed DOWN -303.77 points or -0.63%, the S&P closed DOWN -50.74 points or -0.74% while the Nasdaq closed DOWN -177.089 points or -0.76%
  • Tuesday: The Dow closed DOWN -94.87 points or -0.20%, the S&P closed DOWN -9.50 points or -0.14% while the Nasdaq closed DOWN -55.27 points or -0.24%
  • Monday: The Dow closed DOWN -249.04 points or -0.51%, the S&P closed DOWN -24.20 points or -0.35% while the Nasdaq closed DOWN -118.748 points or -0.50%
  • Last Friday: The Dow closed DOWN -20.19 points or -0.04%, the S&P closed DOWN -2.11 points or -0.03% while the Nasdaq closed DOWN -20.2 points or -0.09%
  • Last week: The S&P 500 was down -1.2%, the Dow was down -1.3% and the Nasdaq was down -1.5%.
  • The previous week: The S&P 500 was up +1.4%, the Dow +1% and the Nasdaq was also up +0.1%
  • December ended with the S&P 500 up +16.4%, the Dow +13% and the Nasdaq +20.4%

 

Q1/26 – Q1 – 1 holiday and 1 positive close  

Q4 –

  • December,1 holiday, 8 positive and 12 negative closes
  • November, 1 holiday, 8 positive and 11 negative sessions
  • October, 1 neutral, 10 positive and 12 negative closes

 

Companies in my headlights – It’s your decision; I provide ideas and context

I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths.  A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.

Thursday was New Years Day and a holiday

Capricor Therapeutics (CAPR) closed down -$0.55 (-1.91% to $28.31) after Wednesday’s -$1.03, Tuesday’s -$0.15, Monday’s +$0.35 and Friday’s +$0.01 (having been down -$0.27) with a negative -$0.39 or -1.38% pre-open - SELL

  • I am STICKING to my CONVICTION that CAPR is overbought and whose valuation is disconnected from fundamentals.
  • Doubts still abound re: regulatory fragility and marginal HOPE-3 results and valuation concerns remain a key hang-up!
  • CAPR remains a structurally challenged, chronically unprofitable company whose valuation is disconnected from fundamentals.
  • It has begun; timing will be everything!
  • The higher CAPR rises, the steeper the fall!

Vertex (VRTX) closed down -$1.23 with a negative -$2.13 or -0.47% pre-open

 

The BOTTOM LINE: Welcome to my world of defining the “grey’ in our universe!

The Santa Claus rally" — during the last 5 trading days of December and first 2 of January — has so far sputtered.

 

January - 1st sessions ...

  • 1 /2 Friday closed positive with 18 incliners, 17 decliners and 5 flats
  • 1/1 -Thursday was a holiday, New Years Day

Last week of December, Q4 and FY25

  • Wednesday closed negative with 18 positive, 22 negative and 5 flats
  • Tuesday closed negative with 7 positive, 31 negative and 2 flats
  • Monday closed negative with 12 positive, 24 negative and 4 flats

 

As the leading voice of cell and gene therapy investors; I am NOT always a doom and gloom analyst/journalist but a man who has been “there” (BUY, SELL, VC and multiple operating roles) with the gray hair and a readership following with real numbers to prove it!

  • I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.  Regulation Analyst Certification (Reg AC):

The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and it’s or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed.