January 29, 2026 7:54am
Stock futures were marginally higher Thursday as traders “speculate” over earnings reports from tech firms weighted by the Fed rate decision
Although I consider caution with a little pessimism sprinkled-on …
Pre-open Signals: Passing today; If you understand probabilities, the inevitable is easier to maneuver
Never leave retail investor uninformed … I say what others won’t, so you can do what others can’t!
I make a commitment to provide need-to-know “facts in evidence” as an equity’s volatility is one tactical signal for stocks. My thesis is important in trying to distinguish the temporary from real pricing digression or progress
RMi Closing Bell: No rate change affects “our” universe needs to capitalize as rates matter … https://www.regmedinvestors.com/articles/14287
I chose to speak-up when many analysts, brokers and commentators have shut-up!
Thursday: The pre-open Dow futures are UP +0.06% or (+28 points), the S&P futures are UP +0.15% or (+10 points) and the Nasdaq futures are UP +0.03% or (+7 points)
- U.S. stock futures are” inching” toward a high, Thursday, 1/29
- European markets opened higher
- Asia Pacific markets were mostly higher
Economic Data: Heavy
- 8:30 am Initial jobless claims Jan. 24 205,000 200,000
- 8:30 am U.S. trade deficit (delayed report) Nov. -$42.9B -$29.4B
- 8:30 am U.S. productivity (revised) Q3 4.9% 4.9%
- 10:00 am Wholesale inventories (delayed report) Nov. 0.2% 0.2%
- 10:00 am Factory orders (delayed report)
Henry’omics: We need to more than consider the market’s setting to grasp the micro re “our” universe of cell and gene therapy companies
- Wednesday: The Dow closed UP +12.37 points or +0.03%, the S&P closed DOWN -0.56 points or -0.01% while the Nasdaq closed UP +40.349 points or +0.17%
- Tuesday: The Dow closed DOWN -409.11 points or -0.83%, the S&P closed UP +28.34 points or +0.41% while the Nasdaq closed UP +215.742 points or +0.91%
- Monday: The Dow closed UP +313.69 points or +0.64%, the S&P closed UP +34.69 points or +0.50% while the Nasdaq closed UP +100.112 points or +0.43%
- Last week: The S&P 500 was down -0.4%, the Dow -0.5% and the Nasdaq was down -0.1%.
- The previous week: The S&P 500 was down -0.4%, the Dow -0.3% and the Nasdaq was down -0.7%.
Q1/26 – Q1 – 2 holiday, 2 neutral, 8 negative and 8 positive closes
Q4 – December,
- 1 holiday, 8 positive and 12 negative closes
- November, 1 holiday, 8 positive and 11 negative sessions
- October, 1 neutral, 10 positive and 12 negative closes
Companies in my headlights – It’s your decision; I provide ideas and context
I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths. A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.
- Passing, could be wrong …but no cards
The BOTTOM LINE: Welcome to my world of defining the “grey’ in our universe!
Caution with a little pessimism sprinkled-on …
- Our “sector” is determined by others … Tesla, Microsoft and Meta headlined huge earnings late after the stock market paused at record highs.
- Less than one month into 2026, Apple (NASDAQ: AAPL) is already down 8.8% year to date at the time
Since, the Q4 and FY25 earnings cycle is about to appear beginning 2/5 and 2 more on 2/14
- 2/5 – Arrowhead Pharmaceuticals (ARWR)
- 2/5 – IQVA Holdings (IQV)
- 2/12 - Vertex (VRTX)
- 2/13 – Moderna (MRNA)
Welcome to my world of defining the “grey’ in our universe!
- I hate to be so negative or contrarian but, this is a NO spin zone and facts and truth are its products; I can always be WRONG but, I am mostly EARLY!
- if I wanted to be liked, I wouldn’t have been an analyst/journalist.
January – 5th week: sector view of my 40 "covered" companies
- 1/28 - Wednesday closed negative with 4 incliners, 35 decliners and 1 flat
- 1/27 - Tuesday closed positive with 21 incliners, 19 decliners and 0 flat
- 1/26 -Monday closed positive with 19 incliners, 18 decliners and 3 flats
January 4rd Week: watching the alternation
- 1/23 – Friday closed negative with 6 incliners, 33 decliners and 1 flat
- 1/22 – Thursday closed positive with 33 incliners, 6 decliners and 1 flat
- 1/21- 1/21 – Wednesday closed positive with 33 incliners, 6 decliners and 1 flat
- 1/20 - Tuesday closed negative with 16 incliners, 22 decliners and 2 flats
- 1/19 – Monday was a holiday, MLK, Jr Day
As the leading voice of cell and gene therapy investors; I am NOT always a doom and gloom analyst/journalist but a man who has been “there” (BUY, SELL, VC and multiple operating roles) with the gray hair and a readership following with real numbers to prove it!
- I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.
Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.
Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors. All investments are subject to risks. Investors should consider investment objectives. Regulation Analyst Certification (Reg AC):
The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and it’s or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed.


