April 24, 2026 7:38am

More of the same, extensions spread uncertainty

Yet, “uncle algo and his electronic trading dwarfs” are lookin to possess after Thursday’s “whack”

Never leave retail investor uninformed … I say what others won’t, so you can KNOW what others can’t!

Let’s see how the geo-pollical and macro news “plays out”

 

Say/write less, mean more …

Thursday’s RMi Closing Bell: Uncertainty, oil pricing, unexpected higher jobless claims’ push sector’s retreat … https://www.regmedinvestors.com/articles/14393

I chose to speak-up when many analysts, brokers and commentators have shut-up!

 

Remember that overnight action in futures don't necessarily translate into actual trading in today’s regular stock market session.

 

Friday: The pre-open Dow futures are UP +0.12% or (+61 points), the S&P futures are UP +0.54% (+38 points) and the Nasdaq futures are UP +1.49% or (+400 pints)

·         U.S. stock futures were positive, Friday, 4/24

·         European equities and bourses bounded lower

·         Asia Pacific markets were mixed

Economic Data: It’s still all about oil pricing

·         10:00 am Consumer sentiment (final)    April     

 

Henry’omics: We need to more than consider the market’s setting to grasp the micro re “our” universe of cell and gene therapy companies

·         Thursday: The Dow closed DOWN -179.71 points or -0.36%, the S&P closed DOWN -29.50 points or -0.41% while the Nasdaq closed DOWN -219.063 points or -0.89%

·         Wednesday: The Dow closed UP +340.65 points or +0.69%, the S&P closed UP +73.89 points or +1.05% while the Nasdaq closed UP +397.603 points or +1.64%

·         Tuesday: The Dow closed DOWN -293.18 points or -0.59%, the S&P closed DOWN -45.13 points or -0.63% while the Nasdaq closed DOWN -144.429 points or -0.59%

·         Monday: The Dow closed DOWN -4.87 points or -0.01%, the S&P closed DOWN -16.91 points or -0.24% while the Nasdaq closed DOWN -64.087 points or -0.26%

·         Last Friday: The Dow closed UP +868.71 points or +1.79%, the S&P closed UP +84.78 points or +1.20% while the Nasdaq closed UP +365.776 points or +1.52%

·         Last week: The S&P gained +3.6%, the Dow +3% and the Nasdaq ascended +4.7%

·         The previous week: the S&P advanced +3.4%, the Dow rose +3% and the Nasdaq dived -1.59%

 

Q2/26 – 1 neutral, 6 negative, 8 positive closes and 1 holiday

  • Q1 – March – 9 positive and 13 negative closes
  • February – 1 market holiday, 11 positive and 8 negative closes
  • January – 2 holiday, 2 neutral, 9 negative and 9 positive closes 

 

Companies in my headlights – It’s your decision; I provide ideas and context

I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths.  A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.

  • Watch and Wait

The BOTTOM LINE: Welcome to my world of defining the “grey’ in our universe!

Reiterating again, investors can a tank through the gaps in sentiment; the S&P 500 is at an all-time high, while consumer sentiment is at an all-time low.

  • Thursday’s reversal from all-time highs showed that headlines coming from the Middle East still can sway the market, even as traders attempt to look past the conflict and focus on corporate earnings reports.

 

Q1/26 Earnings Release Dates:

·         AxoGen (AXGN) – Tuesday, 4/28Alnylam Pharmaceuticals (ALNY) -Thursday, 4/30

·         IQVIA Holdings (IQV) and Supernus Therapeutics (SUPN) – Tuesday, 5/5

·         Vericel (VCEL) – Thursday, 5/7

 

Welcome to my world of defining the “grey’ in our universe!

·         I hate to be so negative or contrarian but, this is a NO spin zone and facts and truth are its products; I can always be WRONG but, I am mostly EARLY!

·         if I wanted to be liked, I wouldn’t have been an analyst/journalist.


April 4th Week:

·         4/23 - Thursday closed negative with 7 incliners, 30 decliners and 3 flats

·         4/22 – Wednesday closed positive with 30 incliners, 9 decliners and 1 flat

·         4/21 – Tuesday closed negative with 5 incliners, 33 decliners and 2 flats

·         4/20 - Monday closed negative with 16 incliners, 21 decliners and 3 flats

 

As the leading voice of cell and gene therapy investors; I am NOT always a doom and gloom analyst/journalist but a man who has been “there” (BUY, SELL, VC and multiple operating roles) with the gray hair and a readership following with real numbers to prove it!

·         I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.  Regulation Analyst Certification (Reg AC):

The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views