November 11, 2015 6:10pm

 

There is no surprise to see stock testing their previous low.

I see tax selling opportunity increasing.

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U.S. stocks ended Wednesday’s thinly-traded session lower as a selloff in energy shares that were triggered by a drop in oil prices weighed on the main indexes. Trading volumes were lower than usual as bond markets and banks are closed in observance of Veterans Day.

The NASDAQ closed DOWN -16.22 or -0.32% to 5,067.02 and the DOW or -55.99 or -0.32% to 17,702.22.

 

 

Henry’omics:

  • Back to my … sentiment conversations:  Investor naivety and fantasy about some sector “participants” reflect a contrarian indicator. A little pessimism is good for stocks, while excessive optimism tends to be negative for stocks;
  •  Paradoxically, a lack of investor sentiment enables sellers generating an influx of traders … and extends the life of this carousel oriented sector mechanics lacking any expectation.

The stem, cell and gene therapy RegMed sector opened negative flipped to the upside by 1 (of 43 covered companies) to close in negative territory

  • My fear gauge – The CBOE Volatility Index (VIX) closed Wednesday near 16 having barely moved on Tuesday to near 15 from Monday’s below 15 following Friday’s above 16.

 

 

A day in the life of the stem, cell and gene therapy RegMed (SCGT & RM) sector:

  • The SCGT & RM equities opened negative with an Advance/Decline line (A/DL) of 14/26 and 3 flats;
  • The mid-day popped to a positive A/DL of 20/19 and 4 flats;
  • The closing bell rang negative to end the session with an A/DL of 14/27 and 2 flats.

 

 

Tuesday’s trading indications:  3 hits/ 2 miss

  • Bellicum Pharma (BLCM) closed UP – hit;
  • Kite Pharma (KITE) closed DOWN – miss;
  • Opexa (OPXA) closed UP - hit;
  • Osiris (OSIR) closed UP – hit;
  • Verastem (VSTM) closed DOWN – miss;

 

 

Riding the indexes and ETFs roller-coaster:

  • The iShares Biotechnology Stocks ETF (IBB) closed DOWN on Wednesday -5.11 or -1.54% after Tuesday’s +1.38 or +0.42% following Monday’s advance of +0.34 or +0.10%;
  • The NASDAQ Biotechnology index (NBI) closed DOWN -49.32 or -1.42% after Tuesday‘s advance of 13.99 or +0.40% following Monday’s advance of +2.30 or +0.07%;
  • The Russell 2000 (IWM) closed DOWN on Wednesday -1.03 or -0.87% after Tuesday’s +0.35 or +0.30% following Monday’s decline of -1.40 or -1.17%;
  • The SPDR SD&P Biotech ETF (XBI) closed DOWN -1.20 or -1.69% on Wednesday after Tuesday’s decline of  -0.25 or -0.35% following Monday’s advance of +0.63 or +0.89%;

 

 

Dosing the sector – what a day for the 43 Patients:

  • Open: NEGATIVE with 26 decliners, 14 advances and 3 flats;
  • Mid-day (1 pm): POSITIVE with 19 decliners, 20 advancers and 4 flats;
  • Closing bell: NEGATIVE with 24 decliner, 17 advancers and 2 flats

 

 

Who was UP – top 5:

  • Regenxbio (RGNX) closed up +$1.45 to $22.98;
  • uniQure (QURE) +$1.03 to $20.57;
  • Spark Therapeutics (ONCE) +$0.55 to $60.26;
  • Juno Therapeutics (JUNO) +$0.45 to $52.28;
  • Osiris (OSIR) closed up +$0.29 to $14.63

 

 

Who closed down – top 5:

  • Aduro Biotech (ADRO) closed down -$1.62 to $28.26;
  • Intrexon (XON) -$1.04 to $41.76;
  • Kite Pharma (KITE) -$1.03 to $61.64;
  • Bluebird bio (BLUE) -$0.93 to $74.30;
  • Cellectis ADR (CLLS) closed down -$0.60 to $37.03;

 

 

Flat:

  • Stemline (STML) at $8.96;
  • Mesoblast ADR (USOTC: MBLTY) at $12.33;

 

 

All investments are subject to risks. Investors should consider investment objectives. The information included above as well as individual companies and/or securities mentioned should only construed as an indication from any RMi reviews.

The facts stated and the opinions given in this publication are based on data and information considered to be reliable and have been carefully worked into my analyses and prognoses. However, no guarantee can be given as to their fairness, accuracy or completeness.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.