March 9, 2017 1:00pm


Entitled Mechanical properties and structure-function relationships of Human Chondrocyte-Seeded Cartilage constructs after In Vitro culture

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The initial data were presented at the Orthopaedic Research Society annual meeting in 3/16 and are based on a long-standing cooperative research agreement between Histogenics and Cornell.


The Bottom Line: The results of the study suggest that in vitro cartilage constructs, or tissue implants, produced using a process that is designed to mimic that of NeoCart exhibited mechanical properties prior to implantation approaching such properties of native cartilage.

Specifically, the results of the study indicate that a combination of cells, scaffold and engineering play an important role in the development of tissue engineered-cartilage implants, such as NeoCart, and the maturation of such implants, leads to improved biological and mechanical properties.

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