Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
May 14, 2015
RegMed the usual “suspects “sputter
May 12, 2015
RegMed, sentiment is not black or white, but always shades of gray
May 11, 2015
RegMed, low volume and fluctuating velocity stems from a reluctance to stand in front of any trade
May 8, 2015
RegMed hopscotches to retrieve share pricing
May 5, 2015
RegMed, back to sell-offs – speaks to the “State of the Sector”
May 4, 2015
RegMed, up, up and away but, still a throwaway
May 2, 2015
RegMed recovers but, what’s the dosage and protocol for the month
May 1, 2015
RegMed’s mid-day: still has legs if not short
April 30, 2015
RegMed has been taken to the wood shed, again
April 30, 2015
RegMed’s mid-day: vulnerability rising
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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