Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
March 20, 2015
RegMed, a see-saw week swings as time and percentages (%) change
March 20, 2015
RegMed Friday: ‘witching” up, down and down
March 19, 2015
RegMed Thursday: strength, spotty volume and upside momentum
March 18, 2015
RegMed, I hear the whispers but, want to feel the dream in my wallet
March 16, 2015
RegMed Monday: sluggish sector reflects past year earnings, spending, clinical data and “runways”
March 13, 2015
RegMed is a shifting sector with a serious lack of conviction
March 12, 2015
RegMed’s extreme moves
March 12, 2015
RegMed Thursday: a lot of air coming out of trades and pricing
March 12, 2015
Higher open expected; RegMed's continued concerns
March 11, 2015
RegMed fled the fire but, the water damage soaked the sector
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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