Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
December 29, 2014
RegMed slices and dices -not much to chew-on
December 29, 2014
Monday’s RegMed rhythms: 3 more trading days, volume is light, soft and spotty
December 26, 2014
RegMed investors need to own what’s WORKING and NOT be LED by the trading extremes
December 23, 2014
RegMed is mired in a fragile week of low volume
December 23, 2014
Tuesday’s RegMed rhythms: Santa needs to deliver sentiment
December 19, 2014
Friday’s RegMed rhythms: deal the cards - face up!
December 18, 2014
Thursday’s RegMed rhythms: snap, crackle, pop and drop set-up
December 18, 2014
Higher open expected; RegMed’s all clear flag NOT raised yet
December 17, 2014
RegMed’s boom and busts - weekly
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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