Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
October 30, 2014
RegMed‘s quiet day enhances positive movement
October 30, 2014
Thursday’s RegMed rhythms – pennies versus dollars
October 29, 2014
RegMed‘s knee-jerk reaction
October 29, 2014
Wednesday’s RegMed rhythms – “our” universe as a tennis ball!
October 29, 2014
Lower to flat opening expected; RegMed’s tacking
October 28, 2014
Tuesday’s RegMed rhythms – monsters under the bed; volume and liquidity!
October 27, 2014
RegMed‘s fickle adjustments yet, opens and closes positive
October 27, 2014
Monday’s RegMed rhythms – weak on low volume
October 27, 2014
Lower opening expected; RegMed expected to “grind”
October 24, 2014
RegMed: 4 out of 5 for the week is not too shabby
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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