Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
March 27, 2014
Trees don't grow to the sky
March 26, 2014
My trading questions is … pulling the trigger or flipping the finger?
March 25, 2014
Oversold, laggard, underperforming, imbalanced, volatile, weak, overbought and momentum …
March 25, 2014
Complacency has brushed “aside” slippage concerns
March 24, 2014
Speeders and leaders to laggards as NeoStem (NBS) is still the “prettiest” in the queue
March 24, 2014
RegMed’s exhausted that “loving feeling”
March 21, 2014
RegMed is cooling down, again
March 20, 2014
Reflect on the recent RegMed reactions
March 20, 2014
March madness, beyond reminding investors to fill out their brackets
March 19, 2014
Who exhaled?
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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