Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
September 3, 2020
RegMed Investors’ (RMi) closing bell: what’s sustainable in September so far, sector depreciation
September 2, 2020
RegMed Investors’ (RMi) closing bell: what’s beneath all the sector selling
September 1, 2020
RegMed Investors’ (RMi) closing bell: upside evaporates with only four (4) positive moves
August 31, 2020
RegMed Investors’ (RMi) closing bell: rebound
August 28, 2020
RegMed Investors’ (RMi) closing bell: sector spurts from oversold territory, what is investor’s tolerance and where is it on track to be?
August 27, 2020
RegMed Investors’ (RMi) closing bell: frothy and flip-flopping sector provokes a bubble syndrome
August 26, 2020
RegMed Investors’ (RMi) closing bell: the sector exhibits a falling knife
August 25, 2020
RegMed Investors’ (RMi) closing bell: from one downside extreme to the upside antithesis
August 24, 2020
RegMed Investors’ (RMi) closing bell: new highs as sector crashes
August 21, 2020
RegMed Investors’ (RMi) closing bell: not only did sector share pricing slip; add in any iota of relative strength
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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