Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
April 14, 2020
RegMed Investors’ (RMi) pre-open: a negative sector close follows a positive after a negative and so on as the rotation continues
April 11, 2020
Regenerative Medicine Earnings Scorecard - Q4 & FY19
April 9, 2020
RegMed Investors’ (RMi) closing bell: thanks for the upside, sell into the upside strength although volume is low
April 8, 2020
RegMed Investors’ (RMi) closing bell: markets are stuck in the middle of anticipation
April 7, 2020
RegMed Investors’ (RMi) closing bell: markets lose their steam minutes from the close as the sector gets ahead of reality
March 31, 2020
RegMed Investors’ (RMi) closing bell: the cell/gene sector swings neutral as Q1 ends and markets collapse
March 31, 2020
RegMed Investors’ (RMi) pre-open: as the quarter ends, don’t chase the sector’s pricing
March 30, 2020
RegMed Investors’ (RMi) closing bell: the cell/gene therapy sector moves to the upside and stays there
March 27, 2020
RegMed Investors’ (RMi) closing bell: volatility strikes to the heart of cell/gene therapy sector and its sentiment indicator
March 27, 2020
RegMed Investors’ (RMi) pre-open: I’m worried about share pricing sustainability
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
holdMy motto … never leave an investor uninformed! I say today what others won’t, so you can do what others can’t.
My name is Henry McCusker; I endorse these opinions under my own name and with a subscription based membership.
Do you have an opinion you would like to share with us? We would like to hear from you.
Please e-mail us at hwm@regmedinvestors.com.
Editor and Publisher ... Henry McCusker enters his tenth (10th) year at RegMed Investors
© 2026 RegMed Investors (regmedinvestors.com), all rights are reserved.
RegMed Investors (RMi) or Regmedinvestors.com content is the intellectual property of Henry McCusker. Any copying, republication or redistribution of RMI’s content, including by framing or similar means, is expressly prohibited without the prior written consent of Scimitar; who also shall not be liable for any errors or delays in content, or for any actions taken in reliance thereon. For additional information on other Scimitar media services or reposting please email hwm@regmedinvestors.com.
The information included above as well as individual companies and/or securities mentioned should be construed as guidance in RMi reviews.
The facts stated and the opinions given in this publication are based on data and information considered to be reliable and have been carefully worked into my qualitative analyses and prognoses. However, no guarantee can be given as to their fairness, accuracy or completeness.
Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.