Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
December 16, 2021
RegMed Investors’ (RMi) closing bell: it’s better to leave early to avoid the sector’s decline
December 15, 2021
RegMed Investors’ (RMi) closing bell: back in the upside/positive zone
December 14, 2021
RegMed Investors’ (RMi) closing bell: another sector smack down
December 13, 2021
RegMed Investors’ (RMi) closing bell: sector concerns as share pricing tanks, then reshuffles to the upside
December 10, 2021
RegMed Investors’ (RMi) closing bell: sector slips after yesterday’s fall
December 9, 2021
RegMed Investors’ (RMi) closing bell: what a difference a session makes
December 8, 2021
RegMed Investors’ (RMi) closing bell: cashing out beats being cashiered
December 7, 2021
RegMed Investors’ (RMi) closing bell: a bottom was found
December 6, 2021
RegMed Investors’ (RMi) closing bell: welcome to the grind, where the sector rose and shone
December 3, 2021
RegMed Investors’ (RMi) closing bell: the “Limbo Dance” how low can we go?
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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