Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
January 6, 2017
RegMed Investors’ (RMi) closing bell analysis, sector dumps to the downside
January 6, 2017
Flat to lower open expected; RegMed Investors’ (RMi) pre-open, sector backslides as upside is hard to sustain
January 5, 2017
RegMed Investors’ (RMi) closing bell analysis, weakness ripped the upside a new one
January 4, 2017
RegMed Investors’ (RMi) closing bell analysis: how long has upside pricing been sustainable?
December 30, 2016
RegMed Investors’ (RMi) closing bell analysis, with no tailwind, the sector closed down
December 29, 2016
RegMed Investors’ (RMi) closing bell analysis, volatility, low volume and speculative momentum drive downturn
December 28, 2016
RegMed Investors’ (RMi) closing bell analysis, Bada Bing … something that happens predictably …
December 15, 2016
RegMed Investors’ (RMi) closing bell analysis, the fear and greed indicator is up
December 13, 2016
RegMed Investors’ (RMi) closing bell analysis, savvy investors’ trade
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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