Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
October 10, 2016
RegMed Investors’ closing bell analysis, we’re stuck in a period of negative outcomes and fewer positive but, soft catalysts
October 7, 2016
RegMed Investors’ closing bell analysis, how some company’s make-up their own rules until they get caught-up in the regulatory maze!
October 6, 2016
Lower open expected; RegMed Investors’ pre-open, are we ready for pain?
October 5, 2016
RegMed Investors’ closing bell analysis, the sector climbs from a crypt with ascending value
October 3, 2016
Slightly higher open expected; RegMed Investors’ pre-open, momentum has been the basis for any upside
September 30, 2016
RegMed Investors’ closing bell analysis, the month and quarter ends
September 28, 2016
RegMed Investors’ closing bell analysis, sellers take advantage of volatility
September 28, 2016
Lower open expected; RegMed Investors’ pre-open, after a positive close …
September 27, 2016
RegMed Investors’ closing bell analysis, what a ride?
September 26, 2016
RegMed Investors’ closing bell analysis, tonight’s debate will shed some light
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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