Bellicum Pharmaceuticals is a clinical stage biopharmaceutical company focused on discovering and developing novel cellular immunotherapies for various forms of cancer, including both hematological and solid tumors, as well as orphan inherited blood disorders.
BLCM has three product candidates in clinical development: BPX-501, an adjunct T-cell therapy product candidate being evaluated in Phase I/II clinical trials in children and adults following a T-depleted, haploidentical hematopoietic stem cell transplant (HSCT); BPX-601, a GoCAR-T product candidate in Phase I development for solid tumors expressing the prostate stem cell antigen; and BPX-701, a T cell receptors (TCR) product candidate in Phase I development for AML with future development potential for treatment of solid tumors expressing the preferentially-expressed antigen in melanoma.
BLCM has collaboration agreements with Adaptimmune Therapeutics plc to evaluate, develop, and commercialize T-cell therapies; Ospedale Pediatrico Bambino Gesú for the design and development of various T cell immunotherapies; and Academisch Ziekenhuis Leiden for research to discover and validate high-affinity TCR product candidates targeting various cancer-associated antigens.
Bellicum Pharmaceuticals, Inc. was founded in 2004 and is headquartered in Houston, Texas.
January 11, 2020
RegMed Investors’ (RMi) closing bell: as I wrote, the downside slide is starting
January 9, 2020
RegMed Investors’ (RMi) closing bell: many share pricing and valuations are tipping the scales
January 8, 2020
RegMed Investors’ (RMi) closing bell: the sector’s rise defused by lightening of political rhetoric
January 7, 2020
RegMed Investors’ (RMi) closing bell: cell and gene therapy pricing was considered a safe bet on Tuesday
January 3, 2020
RegMed Investors’ (RMi) closing bell: volatility sets the tone for first two trading sessions post a holiday
January 3, 2020
RegMed Investors’ (RMi) pre-open: geo-political strike sharpens the dive
January 2, 2020
RegMed Investors’ (RMi) closing bell: starting the year with another downside rotation from Tuesday’s close
January 2, 2020
RegMed Investors’ (RMi) pre-open: first trading session of New Year
December 31, 2019
RegMed Investors’ (RMi) closing bell: It’s over, 2019 ends with sadness and some glee
December 31, 2019
RegMed Investors’ (RMi) pre-open: ending 2019 sliding down an icy slick driveway
35 companies, 1 interpreter!
Insight, foresight and recommendation
Bellicum Pharmaceuticals (BCLM) - January '18 opened at $9.23, slipping to a low of $6.80 on 1/31 flowed by 2/1's $5.87 yet jumping to $6.60 by 2/16. After the KITE and JUNO acquisitions, many percieve that BLCM could be percieved as an appreciator in 2018 ... We do NEED to remember; the U.S. FDA placed a clinical hold on its lead product candidate BPX-501 that's being assessed as an adjunct T-cell therapy administered after haploidentical hematopoietic stem cell transplant. The hold reportedly stems from three cases of potentially treatment-related encephalopathy (abnormal brain function) that occurred during an ongoing trial. BLCM's shares were down 1/31/18 by 33.5% on heavy volume in response to this news.
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