Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
July 15, 2019
RegMed Investors’ (RMi) closing bell: a new week’s session flutters with low volume
July 12, 2019
RegMed Investors’ (RMi) closing bell: the upside and downside pricing was lean
July 11, 2019
RegMed Investors’ (RMi) closing bell: Insight about share pricing is about understanding perception
July 9, 2019
RegMed Investors’ (RMi) closing bell: the sector flips, flops and drops
June 7, 2019
RegMed Investors’ (RMi) closing bell: oversold sensitivity enhances sector upside
June 6, 2019
RegMed Investors’ (RMi) closing bell: it ain’t easy to make a buck in this sector lately unless you're short
June 6, 2019
RegMed Investors’ (RMi) pre-open: eking out an upside
June 5, 2019
RegMed Investors’ (RMi) closing bell: did or will the dead cat bounce?
May 31, 2019
RegMed Investors’ (RMi) closing bell: it’s good that May is over, RIP
May 30, 2019
RegMed Investors’ (RMi) closing bell: the sector crashed and burned
45 companies, 1 interpreter!
Insight, foresight and recommendation
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