Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
March 5, 2021
RegMed Investors’ (RMi) pre-open: lately markets are more forbidding than Russian roulette
March 4, 2021
RegMed Investors’ (RMi) closing bell: the hole got deeper and bottoms became steeper
February 24, 2021
RegMed Investors’ (RMi) pre-open: a bounce, a pounce or just an ounce of upside needed
February 23, 2021
RegMed Investors’ (RMi) closing bell: a pullback, a reversal, a retest or in many cases just plain old earnings’ season doldrums?
February 23, 2021
RegMed Investors’ (RMi) pre-open: "Sunrise, sunset, swiftly flow the days"
February 22, 2021
RegMed Investors’ (RMi) closing bell: sector sentiment slips a steep slide
February 22, 2021
RegMed Investors’ (RMi) pre-open: big earnings’ week, it’s time to be defensive
February 19, 2021
RegMed Investors’ (RMi) closing bell: Zip-a-dee-doo-dah, zip-a-dee-ay; my, oh, my, what a wonderful session
February 10, 2021
RegMed Investors’ (RMi) closing bell: fiddling on a “risky flooring” – indexes flip-flop, sector falls
35 companies, 1 interpreter!
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