Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
December 14, 2018
RegMed Investors’ (RMi) closing bell: sentiment elevators down while pricing action takes the escalator down
December 13, 2018
RegMed Investors’ (RMi) closing bell: the dumpster was full of share bashed sector equities
December 12, 2018
RegMed Investors’ (RMi) closing bell: the tail of the dog, today’s upside momentum is the product of downside volatility and low volume
December 11, 2018
RegMed Investors’ (RMi) closing bell: don’t be lulled by a false sense of upside
December 10, 2018
RegMed Investors’ (RMi) closing bell: drifting to the upside, carried slowly late in the session by a trading current
December 7, 2018
RegMed Investors’ (RMi) closing bell: what markets give, they also take-away
December 6, 2018
RegMed Investors’ (RMi) closing bell: the sector bounces off Tuesday’s low
December 4, 2018
RegMed Investors’ (RMi) closing bell: How many times, can I be right – more than most!
December 3, 2018
RegMed Investors’ (RMi) closing bell: ASH defines the sector while trade initiatives explain the markets
November 30, 2018
RegMed Investors’ (RMi) closing bell: ending an erratic month
45 companies, 1 interpreter!
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