Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
October 13, 2017
RegMed Investors’ (RMi) closing bell; superstition Friday the 13th
October 12, 2017
RegMed Investors’ (RMi) closing bell; another downside day
October 11, 2017
RegMed Investors’ (RMi) closing bell; sector falters and falls on its face
October 10, 2017
RegMed Investors’ (RMi) closing bell; after anticipating an upside and the mid-day slipping
October 10, 2017
RegMed Investors’ (RMi) pre-open indications; when is enough downside, enough and a whipsaw in the making?
October 9, 2017
RegMed Investors’ (RMi) closing bell; why is it that traders are looking …
October 9, 2017
RegMed Investors’ (RMi) pre-open indications; what are the dynamics in cell therapy investing?
October 6, 2017
RegMed Investors’ (RMi) closing bell; what’s really troubling the sector
October 5, 2017
RegMed Investors’ (RMi) closing bell; the market roars as the sector belches
October 4, 2017
RegMed Investors’ (RMi) closing bell; momentum shifted for the oversold
35 companies, 1 interpreter!
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