Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
December 19, 2016
Higher open expected; RegMed Investors’ (RMi) pre-open; where is the sector headed …
December 16, 2016
RegMed Investors’ (RMi) closing bell analysis, the option witch was on its broom …
December 16, 2016
Flat open expected; RegMed Investors’ (RMi) pre-open; a triple witching Friday
December 15, 2016
RegMed Investors’ (RMi) closing bell analysis, the fear and greed indicator is up
December 15, 2016
Higher open expected; RegMed Investors’ (RMi) pre-open; the market is what it is, but what will it be?
December 14, 2016
RegMed Investors’ (RMi) closing bell analysis, a day of falling knives as any strength was sold into …
December 13, 2016
RegMed Investors’ (RMi) closing bell analysis, savvy investors’ trade
December 6, 2016
Lower open expected; RegMed Investors’ (RMi) pre-open; I ain’t lyin’, risk is a four letter swear word
December 5, 2016
RegMed Investors’ (RMi) closing bell analysis, let’s keep this upside moving further
December 5, 2016
Higher open expected; RegMed Investors’ (RMi) pre-open; coping with an alternating sector and market frothiness
35 companies, 1 interpreter!
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