Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
June 17, 2016
RegMed investors’ closing bell analysis: keeping score
June 16, 2016
RegMed investors’ closing bell analysis: “cry me a river”
June 15, 2016
RegMed investors’ closing bell analysis: as good as it gets?
June 8, 2016
Higher open expected; RegMed investors’ analysis, tails of the tape
June 7, 2016
RegMed investors’ closing bell analysis: blow out
June 7, 2016
Higher open expected; RegMed investor’s analysis, cell therapy is defined as
June 6, 2016
RMi’s closing bell analysis: gorging to the upside from gains in the sector
June 1, 2016
Sangamo (SGMO) – CEO Edward Lanphier retires – Sandy Macrae, Ph.D. named as replacement
May 26, 2016
Regenerative Medicine Earnings Scorecard - Q1/2016 - to date
May 25, 2016
Cash vs. Debt
35 companies, 1 interpreter!
Insight, foresight and recommendation
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