Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
April 28, 2023
RegMed Investors’ (RMi) pre-open: how now brown cow?
April 27, 2023
RegMed Investors’ (RMi) closing bell: the market moved up, the cell and gene therapy sector traveled with it
April 27, 2023
RegMed Investors’ (RMi) pre-open: plug-in and recharge the sector and show me some upside
April 26, 2023
RegMed Investors’ (RMi) closing bell: Uncle algo showed briefly and left early
April 26, 2023
RegMed Investors’ (RMi) pre-open: Uncle algorithm coming to rescue the oversold?
April 25, 2023
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector shillyshallies and then quivers
April 25, 2023
RegMed Investors’ (RMi) pre-open: show me some money, any and more upside
April 24, 2023
RegMed Investors’ (RMi) closing bell: calling the ball on underperforming share pricing, just too many factors to list
April 24, 2023
RegMed Investors’ (RMi) pre-open: the push-pull of April’s share pricing facilitates more uncertainty in the short-term
35 companies, 1 interpreter!
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