Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
May 31, 2022
RegMed Investors’ (RMi) closing bell: difficult to navigate as volatility dives the sector at the month of May ends
May 31, 2022
RegMed Investors’ (RMi) pre-open: Snap, crackle and a non-pop
May 19, 2022
RegMed Investors’ (RMi) closing bell: sector was kicked, but not put on its butt
May 19, 2022
RegMed Investors’ (RMi) pre-open: another session is about to be kicked down the “Street”
May 18, 2022
RegMed Investors’ (RMi) closing bell: Tuesday was a short-lived rally as sector equities plummet Wednesday
May 18, 2022
RegMed Investors’ (RMi) pre-open: let’s not be caught off-guard
May 17, 2022
RegMed Investors’ (RMi) closing bell: enjoying the cell and gene therapy sector high and I didn’t even inhale
May 17, 2022
RegMed Investors’ (RMi) pre-open: not a bouncing sector with better dribbling coming
May 12, 2022
RegMed Investors’ (RMi) pre-open: sector equity’ LOWS need consideration to find a sustainable footing - I can dream!
May 11, 2022
RegMed Investors’ (RMi) closing bell: sector pricing was taken to the woodshed and whupped
35 companies, 1 interpreter!
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