Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
February 10, 2025
RegMed Investors (RMi) Closing Bell: more of the downdraft as earnings will further their draft
February 6, 2025
RegMed Investors (RMi) Closing Bell: breaking a rack in pool, what’s different?
February 1, 2025
RegMed Investors (RMi) Closing Bell: another reverse in a volatile week for the cell and gene therapy sector
January 29, 2025
RegMed Investors (RMi) Closing Bell: a little more of the same
January 28, 2025
RegMed Investors (RMi) Closing Bell: adding to investor agita
January 17, 2025
RegMed Investors (RMi) Closing Bell: the green on the screen as week closes, thankfully
January 16, 2025
RegMed Investors (RMi) Closing Bell: a sector stampede to the downside
January 3, 2025
RegMed Investors (RMi) Closing Bell: 2nd session 2025
January 2, 2025
RegMed Investors (RMi) Closing Bell: first session 2025, cell and gene therapy sector bounced as indexes slumped
December 31, 2024
RegMed Investors (RMi) Closing Bell: lordy, lordy, thanks from above, we’ve had enough
35 companies, 1 interpreter!
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