November 25, 2019 9:11am

I’d be cleaning out my portfolio by early tax selling

Pre-open indications: SKIM/SELL – RENE.L, CRSP and QURE; BUY – VSTM, ALNY, BLUE and SAGE

News: Verastem, Inc. (VSTM pre-open indication : +$0.13 or +11.61%) submitted a Marketing Authorization Application to the European Medicines Agency (EMA) for COPIKTRA® (duvelisib), an oral inhibitor of phosphoinositide 3-kinase (PI3K), seeking approval for the treatment of patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and relapsed or refractory follicular lymphoma (FL).

Who is feeding your portfolio intel - profit from RMi’s analysis!


It’s an honor to be considered the “canary in the (sectors) coal mine”!  I post about “indication intelligence” devoting my time to collection and analysis of information to assist investors in the perception of sector vulnerabilities and strengths – it’s more than opinion, the facts and truth need to be recognized!


Dow futures are UP +0.26% (+72 points), S&P futures are UP +0.27% (+9 points) and NASDAQ futures are UP +0.39% (+32 points)


U.S. stock index futures were slightly higher Monday morning;

European markets traded higher on Monday morning with the pan-European Stoxx 600 climbing +0.7% in morning trade;

Asia Pacific shares were higher, reacting to Hong Kong’s district council elections amid months of civil unrest in the city while Mainland Chinese markets were mixed;


Data Docket: Dallas Fed manufacturing figures for November will be released at around 10:30 a.m. ET.



Sector focus is keeping pricing stabilized and any upside sustainable.

Market focus is largely attuned to global trade developments, as investors continue to closely monitor a long-running dispute between the world’s two largest economies.


Friday night’s newsletter heading: “a messy week ends on a positive note. I keep saying, keep skimming the upside taking profit off the table but, understand it doesn’t last yet, there are still “some” BUYs out there. The sector has gotten muddled luckily, being played by the machine trading.”

  • The NASDAQ closed up +13.67 points (+0.16%)
  • The IBB closed up +1.11% while the XBI closed up +0.51%
  • The range of the 27 upside was +0.23% (CLLS) to +24.75% (VSTM +$0.22) while the 14 downside ranged from -0.05% (ONCE) to -4.35% (BSTG); 
  • 8 out of the 27 upside had higher than the 3 month average volume;
  • 6 out of the 14 downside had higher than the 3 month average volume;


Review the context of Q4’s market – so far:

  • November has registered 8 positive and 8 negative close;
  • October registered 10 positive, 1 neutral and 14 negative closes;


Companies in my headlights – It’s your decision; I provide an idea and context:

Pre-open indications: SKIM/SELL – RENE.L, CRSP and QURE; BUY – VSTM, ALNY, BLUE and SAGE



Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions in securities referred to in this publication.