August 11, 2022 7:55am

Build cash position on the back of surging share pricing to pay for the spiraling cost of hotdogs - sarcasm

Pre-open indications:  4 Sell into Strength, 3 Negative Indications, and 1 Puff/Pump/Promote – usual suspect <Biostage (BSTG)>

Earnings: Solid Biosciences (SLDB)

RMi outlines a daily bell ringing of “indications” about what you need to know; it’s what could happen or materialize after the opening and what might happen during the session.

I DEVOTE a HUGE amount of time to “reckoning” the geography of my coverage group - it’s more than opinion, I deal in the facts and numbers that back them up.

The 8:00 A.M., ET edition

Remember that overnight and pre-open actions in futures don't necessarily translate into actual trading in the coming day’s session.


Dow futures are UP +0.46% or (+153 points), S&P futures are UP +0.36% (+15 points) and NASDAQ futures are UP +0.27% (+35 points) early in the pre-open – so far,


Stock futures rose on Thursday,

European markets were mixed,

Asia-Pacific markets climbed.



Wednesday’s regular trading session saw all the major indexes rally

The Dow closed UP +535.10 points (+1.63%); the S&P closed UP +87.77 points (+2.13%) while the Nasdaq closed UP +360.88 points (+2.89%)

Economic Data Docket: At 8:30 a.m. ET, the Labor Department will release weekly jobless claims. Initial claims have risen sharply in the past few months, but remains historically low. Also, continuing claims have climbed far less, suggesting workers who are laid off quickly find new jobs. <IBD>

·         July producer price index data is also slated for release.


RegMed Investors’ (RMi) closing bell: “sector surges as algos didn’t want to miss out on inflation number’s slight tick-up.” …


Ebb and flow –

Q3/22 – August – 5 positive and 3 negative close

July -1 holiday, 10 negative and 10 positive closes

Q2/22 –

June – 1 holiday, 9 positive and 11 negative closes

·         May - 11 positive and 10 negative closes

·         April - 1 holiday, 6 positive and 13 negative closes


·         March – 13 negative and 10 positive closes

·         February stats: 11 negative, 8 positive closes and 1 holiday

·         January stats: 2 holidays, 1 neutral, 13 negative and 6 positive closes


Companies in my headlights – It’s your decision; I provide ideas and context:  INDICATIONS

Negative Indication:

AxoGen (AXGN) closed up +$0.56 to $10.00 after Tuesday’s -$0.95 with a negative -$0.20 or +2% pre-open indication,

BioLife Solutions (BLFS) closed up +$3.82 to $24.17 after Tuesday’s -$0.91 with a negative -$0.31 or -1.28% pre-open indication.

uniQure NV (QURE) closed up +$0.51 to $19.53 with a negative -$0.53 or -2.71% pre-open indication,


Sell into Strength:

Chinook Therapeutics (KDNY closed up +$1.02 to $20.51 with a positive +$0.34 or +1.66% pre-open indication.

CRISPR Therapeutics (CRSP) closed up +$3.74 to $78.87 after -$6.26 to $75.13 with a positive +$0.13 or +0.16% pre-open indication,

Intellia Therapeutics (NTLA) closed up $6.13 to $66.54 after Tuesday’s -$3.08 after Monday’s +$0.17 with a negative -$0.01 or -0.02% pre-open indication,

Verve Therapeutics (VERV) closed up +$3.59 to $31.93 after Tuesday’s +$1.17 after Monday’s +$0.50 with a positive +$0.95 or +2.98% pre-open indication,


Puff/Pump and Promote: Maintaining SELL

Biostage (OTCQB: BSTG) closed flat again with 1,620 shares traded after Tuesday’s -$0.45 to $4.55 after being flat on Monday with 92 shares traded after Friday’s flat and last Thursday’s down -$0.40 to $5.00 with 208 shares traded, <3 mo. Average = 938 shares>

·         Its BOD approved on 7/28 amending and restating their Certificate of Incorporation to affect a reverse split of the issued and outstanding common stock at a ratio of not less than 1-for-1.25 and not greater than 1-for-5. What about all those PPM (private placements) as an offering follows?

·         BSTG seems to have the ONLY avenue to finance to utilize non-U.S. Chinese investors? Are we in favor of Beijing funding and continue to control BSTG in our own country? Another question, makes one wonder, Newbridge Securities?

·         How much lipstick is a lot on this pig with an almost 4-year-old IND and NO clinical trial initiation?

·         WATCH and be ready for a BIG reverse of shares to enable offering from multiple private placements as it tries to facilitate an offering with Newbridge Securities?


Will the new CFO get caught-up in the "SPIN" - Puff/Pump/Promote volume and pricing as the voted upon stock reverse takes hold and an offering appears ... with and under Beijjing, China control?



The BOTTOM LINE: I try to keep it simple … and short!

The sector dive was brought-on hitting the downward resistance wall. This could be temporary stop or the start of a bigger retreat. Either way, investors may want to pare exposure and take some partial profits. If it's just a pause, new buying opportunities will soon present themselves.

The Nasdaq has closed up 3 times and 5 times so far this month while the sector closed with 5 positive and 3 negative closes.

·         8/10 - the Nasdaq closed UP +360.88 points (+2.89%)

·         8/9 - the Nasdaq closed DOWN -150.53 points (-1.19%)

·         8/8 - the Nasdaq closed DOWN -13.10 points (-0.10%)

·         8/5 - the Nasdaq closed DOWN -63.02 points (-0.50%)

·         8/4 - the Nasdaq closed UP +52.42 points (+0.41%)

·         8/3 - the Nasdaq closed UP +319.40 points (+2.59%)

·         8/2 - the Nasdaq closed DOWN 20.22 points (-0.16%

·         8/1 - the Nasdaq closed DOWN -21.71 points (-0.18%)

I am also COOLING on upswing ascensions as the electronic trading is very willing and able to pounce on fraction of a second.

Also *** Volume has been low ...


Most reporting sector companies … to date have reported net losses, lagging revenue estimates although AGEN, AXGN, BEAM, BLFS, CRBU, FATE, RGNX and NTLA beat on revenues generating forward motion while ATM use is up.

This earnings continuum was overshadowed by Alnylam Pharmaceuticals (ALNY) clinical news and the possibility of Global Blood Therapeutics (GBT) became an acquisition while many public companies are facing conflicting signs of growth.

Sector equity pricing are trending in a roller coaster fashion. Also, consensus expectations are low.

We always need a … villain and they are multiplying – low volume as “Earnings’ season is here and now, investors NEED to focus on LPS (loss-per-share), trial status, product revenues, collaboration revenues and cash positions i.e., runways”.

This week: Brainstorm Cell Therapeutics on 8/15, Monday … to date.

As I have written, “It’s STILL nice to be RIGHT” about the direction of the sector having “DEVOTED a HUGE amount of time to “reckoning” the geography of my coverage group.”

Whether information or intelligence is good, bad or somewhere in between; RMi’s daily report is a primer that may say little or a lot; yet it serves as insurance that all indications are being examined and evaluated.


Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

All investments are subject to risks. Investors should consider investment objectives.

Regulation Analyst Certification (Reg AC): The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and its or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed in this report.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions securities referred to in this publication.