February 3, 2026 7:42am
They’re lurking, will “uncle algo and his electronic trading dwarfs” are hungry
Cause and effect coming volatility
Pre-open Signals: passing on prediction, not a good “prognosis” today; If you understand probabilities, the inevitable is easier to maneuver
Never leave retail investor uninformed … I say what others won’t, so you can do what others can’t!
“I hate to be considered negative or contrarian but, this is a NO spin zone and truth is its product; I can always be WRONG but, I am mostly EARLY!”
I chose to speak-up when many analysts, brokers and commentators have shut-up!
Monday’s RMi Closing Bell: Groundhog Day predictions, it’s cold out there … https://www.regmedinvestors.com/articles/14293
Tuesday: The pre-open Dow futures are UP +0.01% or (+7 points), the S&P futures are UP +0.25% or (+17 points) and the Nasdaq futures are UP +0.53% or (+36 points)
- U.S. stock futures are mixed on Tuesday, 2/3
- European markets driving positive,
- Asia Pacific markets rose after President Trump said India had struck a trade deal.
Economic Data: Job openings - Dec.; S&P final U.S. services PMI - Jan. and ISM services
Henry’omics: We need to more than consider the market’s setting to grasp the micro re “our” universe of cell and gene therapy companies
- Monday: The Dow closed UP +515.19 points or +1.05%, the S&P closed UP +37.41 points or +0.54% while the Nasdaq closed UP +130.292 points or +0.56%
- Friday: The Dow closed DOWN -179.09 points or -0.36%, the S&P closed DOWN -29.98 points or -0.43% while the Nasdaq closed DOWN -223.305 points or -0.94%
- Last week: The S&P 500 closed up +0.04% and the Nasdaq -0.2%, while the Dow dropped -0.2%.
- The previous week: The S&P 500 was down -0.4%, the Dow -0.4% and the Nasdaq was down -0.1%.
- January: The S&P 500, Dow were up more than 1% and the Nasdaq had a 0.7% gain.
Q1/26 – Q1 February – 1 positive close
- January – 2 holiday, 2 neutral, 9 negative and 9 positive closes
Q4 – December,
- 1 holiday, 8 positive and 12 negative closes
- November, 1 holiday, 8 positive and 11 negative sessions
- October, 1 neutral, 10 positive and 12 negative closes
Companies in my headlights – It’s your decision; I provide ideas and context
I post about “indication intelligence” looking toward investment conferences … to assist investors with insight into sector vulnerabilities and strengths. A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.
- Many earnings this week and the beginning of sector releases
The BOTTOM LINE: Welcome to my world of defining the “grey’ in our universe ...
To me, it's an Abbott & Costello day; A question of timing ...Who is on first, what's on second ... I am certainly in the dark!
Since, the Q4 and FY25 earnings cycle is about to appear beginning 2/5 and 2 more on 2/14
- 2/5 – Arrowhead Pharmaceuticals (ARWR)
- 2/5 – IQVA Holdings (IQV)
- 2/12 - Vertex (VRTX)
- 2/13 – Moderna (MRNA)
Welcome to my world of defining the “grey’ in our universe!
- I hate to be so negative or contrarian but, this is a NO spin zone and facts and truth are its products; I can always be WRONG but, I am mostly EARLY!
- if I wanted to be liked, I wouldn’t have been an analyst/journalist.
February begins …
- Monday closed positive with 29 incliners, 10 decliners and 1 flat
January – the last week:
- 1/30 – Friday closed negative with 6 incliners, 32 decliners and 2 flat
- 1/29 - Thursday closed positive with 22 incliners, 17 decliners and 1 flat
- 1/28 - Wednesday closed negative with 4 incliners, 35 decliners and 1 flat
- 1/27 - Tuesday closed positive with 21 incliners, 19 decliners and 0 flat
- 1/26 -Monday closed positive with 19 incliners, 18 decliners and 3 flats
As the leading voice of cell and gene therapy investors; I am NOT always a doom and gloom analyst/journalist but a man who has been “there” (BUY, SELL, VC and multiple operating roles) with the gray hair and a readership following with real numbers to prove it!
- I am more frequently right than consequentially wrong; if I wanted to be liked, I wouldn’t have been an analyst/journalist.
Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.
Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors. All investments are subject to risks. Investors should consider investment objectives. Regulation Analyst Certification (Reg AC):
The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and it’s or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed.


