Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
November 16, 2017
RegMed Investors’ (RMi) pre-open indications; covering the bases
November 15, 2017
RegMed Investors’ (RMi) closing bell; today’s sector and market are …
November 15, 2017
RegMed Investors’ (RMi) pre-open indications; flack vest or a checkbook?
November 14, 2017
RegMed Investors’ (RMi) closing bell; in the tank with more loss-per-share quarterly results
November 13, 2017
RegMed Investors’ (RMi) closing bell; sector opens down, swings north at the mid-day, dives around 3 and closes to the downside
November 10, 2017
RegMed Investors’ (RMi) closing bell; some of yesterday’s ups continue to aspire
November 10, 2017
RegMed Investors’ (RMi) pre-open indications; it’s time for a break …
November 9, 2017
RegMed Investors’ (RMi) closing bell; sector opens down, pops at 11:30 am and closes positive
November 9, 2017
RegMed Investors’ (RMi) pre-open indications; is there a pricing at which a share value’s sustainable
November 8, 2017
RegMed Investors’ (RMi) closing bell; no evidence of bottom yet
35 companies, 1 interpreter!
Insight, foresight and recommendation
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