Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
September 11, 2017
RegMed Investors’ (RMi) pre-open indications; there’s no escape
September 8, 2017
RegMed Investors’ (RMi) closing bell; the sector opened up and by 2:30 pm was neutral closing positive
September 8, 2017
RegMed Investors’ (RMi) pre-open indications; long or gone over this weekend
September 7, 2017
RegMed Investors’ (RMi) closing bell; the daily ride on the sector seesaw
September 7, 2017
RegMed Investors’ (RMi) pre-open indications, even expectation is in the air
September 6, 2017
RegMed Investors’ (RMi) closing bell; this week, Verastem’s (VSTM) results driven upside causes a sector weakness thread
September 6, 2017
RegMed Investors’ (RMi) pre-open indications, looking down the barrel at a shot-up sector
September 5, 2017
RegMed Investors’ (RMi) closing bell; another bubble has burst
September 5, 2017
RegMed Investors’ (RMi) pre-open indications, some high premiums since 8/17/17
September 1, 2017
RegMed Investors’ (RMi) closing bell; cell and gene therapy equities are slow movers or down
35 companies, 1 interpreter!
Insight, foresight and recommendation
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