Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
September 1, 2017
RegMed Investors’ (RMi) pre-open indications, keep an eye on the indexes and averages
August 31, 2017
RegMed Investors’ (RMi) closing bell; the sector was rising
August 30, 2017
RegMed Investors’ (RMi) closing bell; Novartis (NVS) moves today’s sector
August 30, 2017
RegMed Investors’ (RMi) pre-open indications, probability is my key word
August 29, 2017
RegMed Investors’ (RMi) closing bell; buying opportunities?
August 29, 2017
RegMed Investors’ (RMi) pre-open indications, expect a reversal
August 28, 2017
RegMed Investors’ (RMi) closing bell; Gilead (GILD) makes a timely, expensive and plucky deal to diversify
August 24, 2017
RegMed Investors’ (RMi) closing bell; here we go again…
August 23, 2017
RegMed Investors’ (RMi) closing bell; sector was up
August 22, 2017
RegMed Investors’ (RMi) closing bell; today’s bounce back sector is …
35 companies, 1 interpreter!
Insight, foresight and recommendation
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