Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
August 9, 2017
Regenerative Medicine Earnings Scorecard - Q2/2017 - to date
August 8, 2017
RegMed Investors’ (RMi) closing bell, is cell therapy losing its individual investor base
August 4, 2017
RegMed Investors’ (RMi) closing bell, sector ends up for second session out of six closes
August 3, 2017
RegMed Investors’ (RMi) closing bell, the sector is turning after a slim positive close of the advance/decline lines
August 1, 2017
RegMed Investors’ (RMi) closing bell, a continued rotation to the downside
July 28, 2017
RegMed Investors’ (RMi) closing bell, the sector flip-flops as expected
July 28, 2017
RegMed Investors’ (RMi) pre-open indications, too many potholes
July 25, 2017
RegMed Investors’ (RMi) closing bell, putting clinical endpoints into perspective
July 17, 2017
RegMed Investors’ (RMi) pre-open indications, the dangers of an alternating sector
July 14, 2017
RegMed Investors’ (RMi) closing bell, momentum with sluggish volume
35 companies, 1 interpreter!
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