Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
July 14, 2017
RegMed Investors’ (RMi) pre-open indications, Friday seems to be a dangerous day …
July 13, 2017
RegMed Investors’ (RMi) closing bell, sector and indexes jockey for altitude
July 12, 2017
RegMed Investors’ (RMi) closing bell, a rising tide
July 11, 2017
RegMed Investors’ (RMi) closing bell, there are just too many fire drills
July 10, 2017
RegMed Investors’ (RMi) pre-open indications, what will today bring …
June 29, 2017
RegMed Investors’ (RMi) closing bell, volatility sweeps the sector
June 28, 2017
RegMed Investors’ (RMi) closing bell, the updraft of the oversold …
June 28, 2017
RegMed Investors’ (RMi) pre-open indications, time to walk
June 27, 2017
RegMed Investors’ (RMi) closing bell, another I told you so …
June 26, 2017
RegMed Investors’ (RMi) closing bell, what news as the sector stays up …
35 companies, 1 interpreter!
Insight, foresight and recommendation
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