Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
June 26, 2017
RegMed Investors’ (RMi) pre-open indications, shovel ready …
June 23, 2017
RegMed Investors’ (RMi) closing bell, staying up with momentum
June 23, 2017
RegMed Investors’ (RMi) pre-open indications, a high?
June 22, 2017
RegMed Investors’ (RMi) closing bell, still in a sprint mode with strong gains
June 22, 2017
RegMed Investors’ (RMi) pre-open indications, the sector runs
June 21, 2017
RegMed Investors’ (RMi) closing bell, some substantial gains
June 21, 2017
RegMed Investors’ (RMi) pre-open indications, the usual irrationality with algo dressing
June 20, 2017
RegMed Investors’ (RMi) closing bell, Icarus is soaring
June 20, 2017
Sangamo Therapeutics (SGMO) proposes $72.5 M offering
June 20, 2017
RegMed Investors’ (RMi) pre-open indications, how long?
35 companies, 1 interpreter!
Insight, foresight and recommendation
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