Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
February 9, 2016
RegMed’s close: turbulence continues with a little “juice” to those with an upside
February 9, 2016
Regenerative Medicine Earnings Scorecard - Q4/2015
February 8, 2016
Sangamo BioSciences (SGMO) FDA Clearance Of IND For ZFN-mediated genome editing treatment
January 29, 2016
RegMed’s close: buying the dips and covering shorts captures short-term momentum and volatility.
January 22, 2016
RegMed’s close: stocks traded higher Friday; it’s time for caution as the oversold rushed a little too quickly upward
January 13, 2016
RegMed’s close: JPM didn’t pass out enough lipstick
December 21, 2015
RegMed’s close: flip, flop who has a drop of Santa Claus sentiment?
December 15, 2015
RegMed’s close: my pattern analysis indicated the sector had to be UP
December 15, 2015
Higher open expected. RegMed’s pre-open, what will today bring ?
December 8, 2015
RegMed’s close: rebound and volatility is not a huge surprise
35 companies, 1 interpreter!
Insight, foresight and recommendation
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