Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
April 7, 2016
RegMed’s close: everything works then, nothing stays
March 21, 2016
RegMed’s close: low to average volatility pushes upside momentum
March 21, 2016
Slightly higher open expected; RegMed sector, do you need a few stock trading clues?
March 7, 2016
RegMed’s close: the fluctuations in “our” universe come any hour, some days and each week
March 2, 2016
Sangamo BioSciences (SGMO) new pre-clinical data in disease models
February 25, 2016
Sangamo BioSciences (SGMO) P2 immunological data from HIV trial
February 23, 2016
RegMed’s close: finding a bottom is a habitual process
February 19, 2016
RegMed’s close postmortem: good to bad to worse to not so bad again
February 10, 2016
RegMed’s close: welcoming the upside
February 10, 2016
Sharply higher open expected, all eyes and ears on Yellen
35 companies, 1 interpreter!
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