Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
September 10, 2015
Sangamo Bioscience (SGMO) approval by the NIH’s Recombinant DNA Advisory Committee of a P1 study protocol for a ZFP Therapeutic for hemophilia B
September 2, 2015
RegMed’s close: stocks jumped, trying to recover from the last two day’s downdraft
September 2, 2015
RegMed’s mid-day: volatility is confusing; we are in a re-testing phase, trade on facts as the news and the trends lose steam too quickly
September 1, 2015
RegMed’s close: “degrossing” taking down the equity risk and exposure while retesting lows
September 1, 2015
RegMed’s mid-day: the vulnerability of the sector is worrisome as technicals are challenged
August 7, 2015
Questionable open expected; RegMed, jobs report roils market movement
August 6, 2015
RegMed’s close: We've had a tough and emotional day +low volume + financial results = extreme volatility
35 companies, 1 interpreter!
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