Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
July 26, 2015
RegMed weekend wrap-up: why should we care what happened last week? It’s a set-up for next week!
July 24, 2015
RegMed’s close: the newest slot machine, a multi-armed bandit
July 24, 2015
RegMed’s mid-day: what’s weighing on the sector – the duration of the downside
July 24, 2015
Higher open expected; RegMed, a week of losses
July 23, 2015
RegMed’s close: timing evaporates strengths
July 18, 2015
RegMed weekend wrap-up: a ladder is needed to climb up and down the tape
July 10, 2015
RegMed, so what can you promise investors – next week?
July 10, 2015
RegMed’s mid-day:headwinds are receding but, still scary
July 9, 2015
RegMed’s reward/risk and return are still weak, hopefully there’s more than a one day bounce
35 companies, 1 interpreter!
Insight, foresight and recommendation
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