Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
January 7, 2022
RegMed Investors’ (RMi) pre-open: will there be a finger that fits in this leaking and spiraling dyke, Hans Brinker where are you?
January 6, 2022
RegMed Investors’ (RMi) closing bell: confluences, a junction of two positions of thought on the cell and gene therapy sector, BUY or SELL?
December 17, 2021
RegMed Investors’ (RMi) closing bell: a cell and gene therapy sector rotation in a frenetic and churning ascension
December 17, 2021
RegMed Investors’ (RMi) pre-open: Quadruple Witching Friday
December 15, 2021
RegMed Investors’ (RMi) closing bell: back in the upside/positive zone
December 14, 2021
RegMed Investors’ (RMi) closing bell: another sector smack down
December 13, 2021
RegMed Investors’ (RMi) closing bell: sector concerns as share pricing tanks, then reshuffles to the upside
December 13, 2021
RegMed Investors’ (RMi) pre-open: an attempt to scale the upside as sector breadth remains a concern after a mixed week
December 10, 2021
RegMed Investors’ (RMi) closing bell: sector slips after yesterday’s fall
35 companies, 1 interpreter!
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