Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
December 23, 2020
RegMed Investors’ (RMi) pre-open: time to enjoy the holidays and stay alive
December 22, 2020
RegMed Investors’ (RMi) closing bell: hi, ho the sector hurdles any downside barriers as Nasdaq reaches a record high after Congress approves virus aid package
December 22, 2020
RegMed Investors’ (RMi) pre-open: staying safe is mitigating perceived risk
December 18, 2020
RegMed Investors’ (RMi) closing bell: sector stiffens with dramatic volume as indexes drop
December 16, 2020
RegMed Investors’ (RMi) closing bell: optimism-based market progress
December 14, 2020
RegMed Investors’ (RMi) closing bell: bumpy roads ahead for equities
December 14, 2020
RegMed Investors’ (RMi) pre-open: follow the bouncing share pricing after Friday’s decline
December 11, 2020
RegMed Investors’ (RMi) closing bell: sentiment takes a dive
December 11, 2020
RegMed Investors’ (RMi) pre-open: after a pop in the sector after Wednesday’s flop, the sector reaches or lingers?
35 companies, 1 interpreter!
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