Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
December 10, 2020
RegMed Investors’ (RMi) closing bell: sector rotates to the upside
December 9, 2020
RegMed Investors’ (RMi) closing bell: a merry-go-round ride
December 8, 2020
RegMed Investors’ (RMi) closing bell: sector’s treading water as momentum relaxes after fresh new market highs
December 7, 2020
RegMed Investors’ (RMi) closing bell: a slip and fall as I had warned
December 7, 2020
RegMed Investors’ (RMi) pre-open: beware of promises of stimulus and vaccine timetables
December 3, 2020
RegMed Investors’ (RMi) closing bell: momentum is like fire; it needs to be fed
December 2, 2020
RegMed Investors’ (RMi) closing bell: the sector rises like a phoenix
November 30, 2020
RegMed Investors’ (RMi) closing bell: indexes dip, sector goes out with a whimper and a positive close
November 25, 2020
RegMed Investors’ (RMi) closing bell: some momentum equities acceded to the falling knife’s theory
November 23, 2020
RegMed Investors’ (RMi) closing bell: vaccine data drives sentiment
35 companies, 1 interpreter!
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