Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
October 5, 2019
RegMed Investors’ (RMi) closing bell: a “goldilocks” upside move
October 4, 2019
RegMed Investors’ (RMi) pre-open: volatility continues spiking
October 3, 2019
RegMed Investors’ (RMi) closing bell: after weakness, there’s neutrality – like today and it is sure to spiral again
October 3, 2019
RegMed Investors’ (RMi) pre-open: I’m employing oversold recognition software to my portfolio
October 2, 2019
RegMed Investors’ (RMi) closing bell: where the sector meets the road too long traveled
September 29, 2019
RegMed Investors’ (RMi) closing bell: another session of sorrow
September 8, 2019
RegMed Investors’ (RMi) closing bell: back to a softening sector as the NASDAQ dips
September 5, 2019
RegMed Investors’ (RMi) closing bell: trade and economic news drives the market higher
September 5, 2019
RegMed Investors’ (RMi) pre-open: another up session on macro and geo-politico trade/tariff talks
September 5, 2019
RegMed Investors’ (RMi) closing bell: from a negative open to a positive close
35 companies, 1 interpreter!
Insight, foresight and recommendation
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