Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
February 1, 2019
RegMed Investors’ (RMi) closing bell: First trading day of new month
January 31, 2019
RegMed Investors’ (RMi) closing bell: The sector surges
January 30, 2019
RegMed Investors’ (RMi) closing bell: investors need to comprehend the refracting light in the prism of share pricing
January 29, 2019
RegMed Investors’ (RMi) closing bell: many see volatility as a measure of risk
January 28, 2019
RegMed Investors’ (RMi) closing bell: retracement is more than a temporary reversal
January 16, 2019
RegMed Investors’ (RMi) closing bell: where is the buzz?
January 15, 2019
RegMed Investors’ (RMi) closing bell: rummaging in the pre-LPS (loss-per-share) earnings time frame
January 14, 2019
RegMed Investors’ (RMi) closing bell: today, it’s about playing the trading ranges after back-to-back negative closes!
35 companies, 1 interpreter!
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